Systemic medications for sickle cell disease and potential applications for sickle cell retinopathy

AK Garg, AW Scott - Current opinion in ophthalmology, 2024 - journals.lww.com
Hydroxyurea has been a mainstay of systemic management of SCD with prior work
suggesting its ability to reduce the likelihood of developing retinopathy. There are several …

Terminology for retinal findings in Sickle Cell Disease Research: a scoping review

GR Reilly, Y Xie, RW Scherer, BS Hawkins… - Ophthalmology …, 2024 - Elsevier
Objective To review the current sickle cell disease (SCD) literature to assess how
“retinopathy” has been defined and to identify ocular outcomes that have been measured …

Routine ophthalmological examination rates in adults with sickle cell disease are low and must be improved

P Zulueta, CP Minniti, A Rai, TJ Toribio… - International journal of …, 2023 - mdpi.com
The American Academy of Ophthalmology and the National Heart, Lung and Blood Institute
recommend patients with sickle cell disease (SCD) undergo dilated funduscopic exams …

Adaptive vessel tracing and segmentation in OCT enables the robust detection of wall-to-lumen ratio abnormalities in 5xFAD mice

T Adejumo, G Ma, T Son, TH Kim, D Le… - Biomedical Optics …, 2023 - opg.optica.org
The wall-to-lumen ratio (WLR) of retinal blood vessels promises a sensitive marker for the
physiological assessment of eye conditions. However, in vivo measurement of vessel wall …

Proliferative Sickle Cell Retinopathy: A Patient and a Physician's Perspective on Quality of Life and Quality of Eye Care

C Taylor, R Awadzi, J Enoch, C Dinah - Ophthalmology and Therapy, 2024 - Springer
The impact of visual impairment in the context of sickle cell disease is poorly understood.
Despite the significant advancements over the past three decades in retinal imaging and in …

Inclusive research in ophthalmology is mission critical! The 10-point action plan

C Dinah, O Williams, D Varma, R Reynolds, PJ Patel… - Eye, 2024 - nature.com
The casual observer may assume that we are winning the battle against vision impairment
and indeed, we are making good progress. However, the rate of progress may be slower …

How I Manage Sickle Cell Retinopathy

CM Ambrosino, AW Scott - Current Surgery Reports, 2024 - Springer
Abstract Purpose of Review We describe our current approach to sickle cell retinopathy
screening, evaluation, treatment, and surgical intervention. Recent Findings Small and …

[HTML][HTML] Salmon patch maculopathy: An amblyogenic complication of pediatric sickle cell retinopathy

N Rao, T McKnight, C Norris, D Scoles - American Journal of …, 2024 - Elsevier
Purpose To report a case of a large foveal sub-internal limiting membrane hemorrhage from
sickle cell retinopathy in a pediatric patient. Observations A five-year-old boy with sickle cell …

Adaptive vessel tracing and segmentation in OCT enables robust detection of wall-to-lumen ratio abnormalities in 5xFAD mice

X Yao, T Adejumo, G Ma, T Son, TH Kim, D Le… - 2023 - preprints.opticaopen.org
The wall-to-lumen ratio (WLR) of retinal blood vessels promises a sensitive marker for
physiological assessment of eye conditions. However, in vivo measurement of vessel wall …

Screening for sickle-cell retinopathy

PT Ashwin, R Sivaraj - Eye, 2023 - nature.com
UK National Screening committee has issued clear guidance for a population screening
programme [2]. The target population to be screened needs to be defined and a database …