The Insula: A Critical Neural Substrate for Drug Seeking under Conflict and Risk
This chapter begins with a summary of the initial findings on the effects of insula lesions on
smoking behavior as well as more recent human‐lesion studies that replicate and extend …
smoking behavior as well as more recent human‐lesion studies that replicate and extend …
The neurocircuitry of impaired insight in drug addiction
More than 80% of addicted individuals fail to seek treatment, which might reflect impairments
in recognition of severity of disorder. Considered by some as intentional deception, such …
in recognition of severity of disorder. Considered by some as intentional deception, such …
Risky business: the neuroeconomics of decision making under uncertainty
ML Platt, SA Huettel - Nature neuroscience, 2008 - nature.com
Many decisions involve uncertainty, or imperfect knowledge about how choices lead to
outcomes. Colloquial notions of uncertainty, particularly when describing a decision as' …
outcomes. Colloquial notions of uncertainty, particularly when describing a decision as' …
A somatic marker theory of addiction
A Verdejo-García, A Bechara - Neuropharmacology, 2009 - Elsevier
Similar to patients with ventromedial prefrontal cortex (VMPC) lesions, substance abusers
show altered decision-making, characterized by a tendency to choose the immediate …
show altered decision-making, characterized by a tendency to choose the immediate …
Striatocortical pathway dysfunction in addiction and obesity: differences and similarities
D Tomasi, ND Volkow - Critical reviews in biochemistry and …, 2013 - Taylor & Francis
Neuroimaging techniques are starting to reveal significant overlap in the brain circuitry
underlying addiction and disorders of dyscontrol over rewarding behaviors (such as binge …
underlying addiction and disorders of dyscontrol over rewarding behaviors (such as binge …
Methamphetamine use causes cognitive impairment and altered decision-making
H Mizoguchi, K Yamada - Neurochemistry international, 2019 - Elsevier
Methamphetamine is a widely abused psychostimulant. It reverses transport through the
dopamine transporter, thereby increasing the extracellular level of dopamine in the brain …
dopamine transporter, thereby increasing the extracellular level of dopamine in the brain …
Insula and drug cravings
H Garavan - Brain structure and function, 2010 - Springer
This paper reviews the role of the insula in drug craving. Evidence is presented that drug
craving may be a particular instance of the anterior insula's broader role in interoception and …
craving may be a particular instance of the anterior insula's broader role in interoception and …
Neural substrates of time perception and impulsivity
Several studies provide empirical evidence for the association between impulsivity and time
perception. However, little is known about the neural substrates underlying this function …
perception. However, little is known about the neural substrates underlying this function …
Reward-related processing in the human brain: developmental considerations
The pursuit of rewarding experiences motivates everyday human behavior, and can prove
beneficial when pleasurable, positive consequences result (eg, satisfying hunger, earning a …
beneficial when pleasurable, positive consequences result (eg, satisfying hunger, earning a …
[HTML][HTML] Neuroeconomic approaches to mental disorders
The pervasiveness of decision-making in every area of human endeavor highlights the
importance of understanding choice mechanisms and their detailed relationship to …
importance of understanding choice mechanisms and their detailed relationship to …