Despite over half a century of research, respiratory syncytial virus (RSV)-induced
bronchiolitis remains a major cause of hospitalisation in infancy, while vaccines and specific …

Motivation The human leukocyte antigen (HLA) locus plays a critical role in tissue
compatibility and regulates the host response to many diseases, including cancers and …

We developed a metatranscriptomics method that can simultaneously capture the
respiratory virome, microbiome, and host response directly from low biomass samples …

Respiratory syncytial virus (RSV) is a major cause of lower respiratory tract infections and
hospital visits during infancy and childhood. Although risk factors for RSV infection have …

Background Data on the host factors that contribute to infection of young children by
respiratory syncytial virus (RSV) are limited. The human chemokine receptor, CX3CR1, has …

Background Recently there has been a growing interest in the potential for host
transcriptomic analysis to augment the diagnosis of infectious diseases. Methods We …

The global assessment of host RNA transcriptional immune responses has improved our
understanding of the host-pathogen interactions in the clinical setting. It has shown the …

Respiratory syncytial virus (RSV) contains a conserved CX3C motif on the ectodomain of the
G protein. The motif has been indicated as facilitating attachment of the virus to the host …

Background Respiratory syncytial virus (RSV) is the leading cause of severe respiratory
disease in infants. The causes and correlates of severe illness in the majority of infants are …

Background Airway epithelial injury is a crucial component of acute and severe asthma
pathogenesis and a promising target for treatment of refractory asthma. However, the …