The development of low molecular weight anion transporters is an emerging topic in
supramolecular chemistry. The major focus of this tutorial review is on synthetic chloride …

α-Helical membrane proteins fulfill many vital roles in all living cells and constitute the
majority of drug targets. However, their relevance is in no way paralleled by our current …

The ion transport activity of calix [4] arene tetrabutylamide 1, 3-alt 2 was studied in
liposomes, planar lipid bilayers, and HEK-293 cells. These experiments, when considered …

Synthetic ion channels that mimic the functions of natural ion channels are of great interest
in chemistry, biochemistry, biology, and materials science. In this paper, we present a novel …

The strychnine‐sensitive glycine receptor is the principal mediator of fast inhibitory synaptic
transmission in the mammalian spinal cord and brain stem. As a member of the ligand …

Synthetic ion channels are of great interest in mimicking the biological functions of natural
ion channels. Although many synthetic ion channels could selectively mediate ion transport …

Mutations in the gene-encoding cystic fibrosis transmembrane conductance regulator
(CFTR) cause defective transepithelial transport of chloride (Cl−) ions and fluid, thereby …

An increasing number of synthetic compounds have been shown to facilitate ion and polar
molecule transport across bilayer membranes. Most notably, recent advances in anion …

Benzimidazolium-based synthetic chloride and calcium transporters in bacterial membranes -
Organic & Biomolecular Chemistry (RSC Publishing) DOI:10.1039/C2OB26966J Royal Society …

Cystic fibrosis (CF), an inherited disease characterized by defective epithelial Cl− transport,
damages lungs via chronic inflammation and oxidative stress. Glutathione, a major …