Retinal ganglion cell repopulation for vision restoration in optic neuropathy: a roadmap from the RReSTORe Consortium

JR Soucy, EA Aguzzi, J Cho, MJ Gilhooley… - Molecular …, 2023 - Springer
Retinal ganglion cell (RGC) death in glaucoma and other optic neuropathies results in
irreversible vision loss due to the mammalian central nervous system's limited regenerative …

Müller Glial Cell–Dependent Regeneration of the Retina in Zebrafish and Mice

J Jui, D Goldman - Annual Review of Genetics, 2024 - annualreviews.org
Sight is one of our most precious senses. People fear losing their sight more than any other
disability. Thus, restoring sight to the blind is an important goal of vision scientists …

VEGF signaling governs the initiation of biliary-mediated liver regeneration through the PI3K-mTORC1 axis

P Cai, R Ni, M Lv, H Liu, J Zhao, J He, L Luo - Cell Reports, 2023 - cell.com
Biliary epithelial cells (BECs) are a potential source to repair the damaged liver when
hepatocyte proliferation is compromised. Promotion of BEC-to-hepatocyte …

[HTML][HTML] Keratin 8/18a. 1 Expression Influences Embryonic Neural Crest Cell Dynamics and Contributes to Postnatal Corneal Regeneration in Zebrafish

AL Williams, BL Bohnsack - Cells, 2024 - mdpi.com
A complete understanding of neural crest cell mechanodynamics during ocular development
will provide insight into postnatal neural crest cell contributions to ophthalmic abnormalities …

Mapping the cellular expression patterns of vascular endothelial growth factor aa and bb genes and their receptors in the adult zebrafish brain during constitutive …

D Fernezelian, S Pfitsch, S Rastegar, N Diotel - Neural Development, 2024 - Springer
The complex interplay between vascular signaling and neurogenesis in the adult brain
remains a subject of intense research. By exploiting the unique advantages of the zebrafish …

Heparin-binding epidermal growth factor and fibroblast growth factor 2 rescue Müller glia-derived progenitor cell formation in microglia-and macrophage-ablated chick …

HM El-Hodiri, JR Bentley, AG Reske… - …, 2023 - journals.biologists.com
Recent studies have demonstrated the impact of pro-inflammatory signaling and reactive
microglia/macrophages on the formation of Müller glial-derived progenitor cells (MGPCs) in …

Brd activity regulates Müller glia‐dependent retinal regeneration in zebrafish

J Lee, BK Lee, JM Gross - Glia, 2023 - Wiley Online Library
The zebrafish retina possesses tremendous regenerative potential. Müller glia underlie
retinal regeneration through their ability to reprogram and generate multipotent neuronal …

Single-cell RNA sequencing reveals the heterogeneity and interactions of immune cells and Müller glia during zebrafish retina regeneration

H Xu, L Cao, Y Chen, C Zhou, J Xu… - Neural Regeneration …, 2024 - journals.lww.com
Inflammation plays a crucial role in the regeneration of fish and avian retinas. However, how
inflammation regulates Müller glia (MG) reprogramming remains unclear. Here, we used …

[HTML][HTML] Telencephalic stab wound injury induces regenerative angiogenesis and neurogenesis in zebrafish: unveiling the role of vascular endothelial growth factor …

D Fernezelian, P Rondeau, L Gence… - Neural regeneration …, 2025 - journals.lww.com
After brain damage, regenerative angiogenesis and neurogenesis have been shown to
occur simultaneously in mammals, suggesting a close link between these processes …

AOP-Anchored Transcriptome Analysis Catalogue Accelerates the Discovery of Environmental Toxicants in Zebrafish

J Chen, C Wang, W Tu, K Zhang, K Fent… - Environmental …, 2024 - ACS Publications
Current toxicity screening approaches to evaluate the vast number of environmental
chemicals that require assessment are hampered due to their significant costs, time …