The bioactive peptide adrenomedullin (AM) exerts pleiotropic actions in various organs and
tissues. In the heart, AM has an inhibitory effect on ventricular remodeling, suppressing …

Adrenomedullin (AM) is a regulatory peptide whose involvement in tumour progression is
becoming more relevant with recent studies. AM is produced and secreted by the tumour …

The current study investigated adrenomedullin as a potential autocrine regulator of
pancreatic cancer cell function. Adrenomedullin was localized in the neoplastic epithelium of …

Simple Summary Neurokinins A and B, adrenomedullin, adrenomedullin 2, amylin, and
calcitonin gene-related peptide are essential in different tumors. These peptides are …

Introduction Adrenomedullin (AM) is secreted by breast cancer cells and increased by
hypoxia. It is a multifunctional peptide that stimulates angiogenesis and proliferation. The …

Adrenomedullin (AM) is a multifunctional 52-amino acid peptide. AM has several effects and
acts as a growth factor in several types of cancer cells. Our previous study revealed that an …

Adrenomedullin blockade suppresses sunitinib-resistant renal cell carcinoma growth by
targeting the ERK/MAPK pathway - PMC Back to Top Skip to main content NIH NLM Logo …

Adrenomedullin (ADM) and hypoxia-inducible factor-1α (HIF-1α) are important pro-
proliferation genes in response to hypoxic stress. Although it was reported that ADM is a …

Introduction Adrenomedullin (AM) is a peptide responsible for many physiological processes
including vascular health and hormone regulation. Dysregulation of AM signaling can …

Importance of the field: Hypoxia, a frequent characteristic in the microenvironment of solid
tumors, leads to adrenomedullin (AM) upregulation through the hypoxia inducible factor-1 …