Biomaterials releasing drug responsively to promote wound healing via regulation of pathological microenvironment

H Li, B Li, D Lv, W Li, Y Lu, G Luo - Advanced Drug Delivery Reviews, 2023 - Elsevier
Wound healing is characterized by complex, orchestrated, spatiotemporal dynamic
processes. Recent findings demonstrated suitable local microenvironments were …

Mimicking biofilm formation and development: Recent progress in in vitro and in vivo biofilm models

I Guzmán-Soto, C McTiernan, M Gonzalez-Gomez… - Iscience, 2021 - cell.com
Biofilm formation in living organisms is associated to tissue and implant infections, and it has
also been linked to the contribution of antibiotic resistance. Thus, understanding biofilm …

Biofilms in diabetic foot ulcers: significance and clinical relevance

C Pouget, C Dunyach-Remy, A Pantel, S Schuldiner… - Microorganisms, 2020 - mdpi.com
Foot infections are the main disabling complication in patients with diabetes mellitus. These
infections can lead to lower-limb amputation, increasing mortality and decreasing the quality …

From in vitro to in vivo Models of Bacterial Biofilm-Related Infections

D Lebeaux, A Chauhan, O Rendueles, C Beloin - Pathogens, 2013 - mdpi.com
The influence of microorganisms growing as sessile communities in a large number of
human infections has been extensively studied and recognized for 30–40 years, therefore …

Polymicrobial interactions: impact on pathogenesis and human disease

BM Peters, MA Jabra-Rizk, GA O'May… - Clinical microbiology …, 2012 - Am Soc Microbiol
Microorganisms coexist in a complex milieu of bacteria, fungi, archaea, and viruses on or
within the human body, often as multifaceted polymicrobial biofilm communities at mucosal …

Staphylococcus aureus Shifts toward Commensalism in Response to Corynebacterium Species

MM Ramsey, MO Freire, RA Gabrilska… - Frontiers in …, 2016 - frontiersin.org
Staphylococcus aureus–human interactions result in a continuum of outcomes from
commensalism to pathogenesis. S. aureus is a clinically important pathogen that …

[HTML][HTML] Polymicrobial infections and biofilms: clinical significance and eradication strategies

VT Anju, S Busi, M Imchen, R Kumavath, MS Mohan… - Antibiotics, 2022 - mdpi.com
Biofilms are population of cells growing in a coordinated manner and exhibiting resistance
towards hostile environments. The infections associated with biofilms are difficult to control …

An In Vivo Polymicrobial Biofilm Wound Infection Model to Study Interspecies Interactions

T Dalton, SE Dowd, RD Wolcott, Y Sun, C Watters… - PloS one, 2011 - journals.plos.org
Chronic wound infections are typically polymicrobial; however, most in vivo studies have
focused on monospecies infections. This project was designed to develop an in vivo …

Community surveillance enhances Pseudomonas aeruginosa virulence during polymicrobial infection

A Korgaonkar, U Trivedi… - Proceedings of the …, 2013 - National Acad Sciences
Most infections result from colonization by more than one microbe. Within such polymicrobial
infections, microbes often display synergistic interactions that result in increased disease …

[HTML][HTML] The polymicrobial nature of biofilm infection

R Wolcott, JW Costerton, D Raoult, SJ Cutler - Clinical Microbiology and …, 2013 - Elsevier
The model of biofilm infection was first proposed over a decade ago. Recent scientific
advances have added much to our understanding of biofilms, usually polymicrobial …