Enantioselective synthesis of 5-methylidenedihydrouracils as potential anticancer agents
M Pięta, J Kędzia, D Kowalczyk, J Wojciechowski… - Tetrahedron, 2019 - Elsevier
An efficient, versatile, enantioselective synthesis of 1, 3-disubstituted and 1, 3, 6-
trisubstituted 5-methylidenedihydrouracils applying Horner-Wadsworth Emmons …
trisubstituted 5-methylidenedihydrouracils applying Horner-Wadsworth Emmons …
[HTML][HTML] New uracil analogs as downregulators of ABC transporters in 5-fluorouracil-resistant human leukemia HL-60 cell line
A Długosz-Pokorska, M Pięta, T Janecki… - Molecular Biology …, 2019 - Springer
Overexpression of ATP-binding cassette (ABC) transporters causing multidrug resistance
(MDR) in cancer cells is one of the major obstacles in cancer chemotherapy. The 5-FU …
(MDR) in cancer cells is one of the major obstacles in cancer chemotherapy. The 5-FU …
Testing intermediates to unravel the mechanism of flavin-dependent thymidylate biosynthesis
D Mondal - 2018 - search.proquest.com
In humans and most eukaryotes, thymidylate synthase (TSase) serves as a key enzyme that
catalyzes the reductive methylation of deoxyuridine monophosphate (dUMP) to synthesize …
catalyzes the reductive methylation of deoxyuridine monophosphate (dUMP) to synthesize …
[引用][C] International Journal of Drug Research and Technology
MO Kamara, MY Wang, X Li, G Lu, S Li, FH Meng - Int. J. Drug Res. Tech, 2019