Anti-melanoma differentiation–associated gene 5 (MDA5) dermatomyositis: a concise review with an emphasis on distinctive clinical features

DJB Kurtzman, RA Vleugels - Journal of the American Academy of …, 2018 - Elsevier
Melanoma differentiation–associated gene 5 (MDA5) is a recently described autoantigen
target in a subset of patients with dermatomyositis. Anti-MDA5 dermatomyositis is …

STING-mediated lung inflammation and beyond

ML Frémond, YJ Crow - Journal of clinical immunology, 2021 - Springer
Mendelian autoinflammatory diseases characterized by constitutive activation of the type I
interferon pathway, the so-called type I interferonopathies, constitute a rapidly expanding …

Recommendations for the treatment of anti-melanoma differentiation-associated gene 5-positive dermatomyositis-associated rapidly progressive interstitial lung …

F Romero-Bueno, PD Del Campo… - Seminars in arthritis and …, 2020 - Elsevier
Objectives The study aimed to develop evidence-based recommendations for the treatment
of rapidly progressive interstitial lung disease (RPILD) associated with the anti-Melanoma …

Anti–melanoma differentiation–associated protein 5–associated dermatomyositis: expanding the clinical spectrum

JC Hall, L Casciola‐Rosen, LA Samedy… - Arthritis care & …, 2013 - Wiley Online Library
Objective Autoantibodies against melanoma differentiation–associated protein 5 (MDA‐5)
have been described in several Asian dermatomyositis (DM) cohorts, often associated with …

[HTML][HTML] IgM anti-ACE2 autoantibodies in severe COVID-19 activate complement and perturb vascular endothelial function

L Casciola-Rosen, DR Thiemann, F Andrade… - JCI insight, 2022 - ncbi.nlm.nih.gov
Background Some clinical features of severe COVID-19 represent blood vessel damage
induced by activation of host immune responses initiated by the coronavirus SARS-CoV-2 …

Anti‐MDA5 antibodies in a large Mediterranean population of adults with dermatomyositis

M Labrador-Horrillo, MA Martinez… - Journal of …, 2014 - Wiley Online Library
A new myositis‐specific autoantibody directed against melanoma differentiation‐associated
gene 5 (anti‐MDA5) has been described in patients with dermatomyositis (DM). We report …

Cutaneous ulceration in dermatomyositis: association with anti–melanoma differentiation–associated gene 5 antibodies and interstitial lung disease

NS Narang, L Casciola‐Rosen, S Li… - Arthritis care & …, 2015 - Wiley Online Library
Objective To identify clinical and serologic correlates of cutaneous ulcers in dermatomyositis
(DM). Methods We retrospectively examined a cohort of 152 DM patients. We compared the …

Clinical utility of an enzyme-linked immunosorbent assay for detecting anti-melanoma differentiation-associated gene 5 autoantibodies

S Sato, A Murakami, A Kuwajima, K Takehara… - PLoS …, 2016 - journals.plos.org
Objective Autoantibodies to melanoma differentiation-associated gene 5 (MDA5) are
specifically expressed in patients with dermatomyositis (DM) and are associated with a …

Dermatomyositis clinical and pathological phenotypes associated with myositis-specific autoantibodies

PW Wolstencroft, DF Fiorentino - Current rheumatology reports, 2018 - Springer
Purpose of review Dermatomyositis is an idiopathic inflammatory myopathy with a variety of
systemic and cutaneous manifestations. The myositis-specific autoantibodies (MSAs) are …

Interstitial lung disease in systemic autoimmune rheumatic diseases: a comprehensive review

F Atzeni, MC Gerardi, G Barilaro, IF Masala… - Expert review of …, 2018 - Taylor & Francis
ABSTRACT Background: Interstitial lung diseases (ILDs) are among the most serious
complications associated with systemic rheumatic diseases, and lead to significant morbidity …