miRNAs as potential game-changers in bone diseases: Future medicinal and clinical Uses

AS Doghish, MS Elballal, O Elazazy… - … -Research and Practice, 2023 - Elsevier
Abstract MicroRNAs (miRNAs), short, highly conserved non-coding RNA, influence gene
expression by sequential mechanisms such as mRNA breakdown or translational …

miRNAs role in glioblastoma pathogenesis and targeted therapy: Signaling pathways interplay

SS Elshaer, AI Abulsoud, D Fathi… - … -Research and Practice, 2023 - Elsevier
High mortality and morbidity rates and variable clinical behavior are hallmarks of
glioblastoma (GBM), the most common and aggressive primary malignant brain tumor …

miRNAs as potential game-changers in head and neck cancer: Future clinical and medicinal uses

HA El-Mahdy, AM Mohamadin, AI Abulsoud… - … -Research and Practice, 2023 - Elsevier
Head and neck cancers (HNCs) are a group of heterogeneous tumors formed most
frequently from epithelial cells of the larynx, lips, oropharynx, nasopharynx, and mouth …

A spotlight on the interplay of signaling pathways and the role of miRNAs in osteosarcoma pathogenesis and therapeutic resistance

AS Doghish, M Hegazy, A Ismail, HA El-Mahdy… - … -Research and Practice, 2023 - Elsevier
Osteosarcoma (OS) is one of the most common bone cancers that constantly affects
children, teenagers, and young adults. Numerous epigenetic elements, such as miRNAs …

The role of miRNAs in the pathogenesis and therapeutic resistance of endometrial cancer: a spotlight on the convergence of signaling pathways

NM Abdelmaksoud, HA El-Mahdy, A Ismail… - … -Research and Practice, 2023 - Elsevier
Endometrial cancer (EC) is the 2nd common cancer in females after breast cancer. Besides,
it's the most common among gynecological cancers. Several epigenetic factors such as …

The interplay of signaling pathways with miRNAs in cholangiocarcinoma pathogenicity and targeted therapy

MB Zaki, AI Abulsoud, SS Elshaer, D Fathi… - … -Research and Practice, 2023 - Elsevier
Cholangiocarcinoma (CCA), the second most frequent liver cancer after hepatocellular
carcinoma, has been rising worldwide in recent epidemiological research. This neoplasia's …

miRNAs as potential game-changers in melanoma: a comprehensive review

GM Abd-Allah, A Ismail, HA El-Mahdy… - … -Research and Practice, 2023 - Elsevier
Melanoma is the sixth most frequent malignancy. It represents 1.7% of all cancer cases
worldwide. Many risk factors are associated with melanoma including ultraviolet radiation …

miRNAs as potential game-changers in renal cell carcinoma: Future clinical and medicinal uses

MS Elballal, AAM Sallam, AE Elesawy… - … -Research and Practice, 2023 - Elsevier
Renal cell carcinoma (RCC) has the highest mortality rate of all genitourinary cancers, and
its prevalence has grown over time. While RCC can be surgically treated and recurrence is …

The interplay of signaling pathways and miRNAs in the pathogenesis and targeted therapy of esophageal cancer

AS Doghish, AA El-Husseiny… - … -Research and Practice, 2023 - Elsevier
Globally, esophageal cancer (EC) is the 6th leading cause of cancer-related deaths and the
second deadliest gastrointestinal cancer. Multiple genetic and epigenetic factors, such as …

The potential role of miRNAs in the pathogenesis of salivary gland cancer–A Focus on signaling pathways interplay

AI Abulsoud, SS Elshaer, AA El-Husseiny… - … -Research and Practice, 2023 - Elsevier
Salivary gland cancer (SGC) is immensely heterogeneous, both in terms of its physical
manifestation and its aggressiveness. Developing a novel diagnostic and prognostic …