WNT signaling is an elaborate and complex collection of signal transduction pathways
mediated by multiple signaling molecules. WNT signaling is critically important for …

The release of reactive oxygen species (ROS) and the generation of oxidative stress are
considered critical factors for the pathogenesis of diabetes mellitus (DM), a disorder that is …

Tumor-associated macrophages (TAMs) are a major component of tumor microenvironment
(TME) and play pivotal roles in the progression of hepatocellular carcinoma (HCC). Wnt …

Inflammation is part of the natural healing response, but persistent inflammatory events tend
to contribute to pathology changes of tendon or ligament. Phenotypic switching of …

As a proliferative and restorative entity, Wnt1 inducible signaling pathway protein 1 (WISP1)
is emerging as a novel target for a number of therapeutic strategies that are relevant for …

Within the last years the implementation of systems biology in nutritional research has
emerged as a powerful tool to understand the mechanisms by which dietary components …

Wnt signaling encompasses multiple and complex signaling cascades and is involved in
many developmental processes such as tissue patterning, cell fate specification, and control …

Low‐density lipoprotein receptor‐related protein 5 (LRP 5) is a member of the LDLR family
that orchestrates cholesterol homoeostasis. The role of LRP 5 and the canonical Wnt …

According to the World Health Organization, diabetes mellitus (DM) in the year 2030 will be
ranked the seventh leading cause of death in the world. DM impacts all systems of the body …

Aims Myocardial infarction induces myocardial injury and tissue damage. During myocardial
infarction strong cellular response is initiated to salvage the damaged tissues. This response …