The incidence of sepsis is highest in neonates and children, yet the global burden of sepsis
in these age groups has not been assessed. We reviewed available evidence from …

For more than two decades, sepsis was defined as a microbial infection that produces fever
(or hypothermia), tachycardia, tachypnoea and blood leukocyte changes. Sepsis is now …

Rationale: Reducing the global burden of sepsis, a recognized global health challenge,
requires comprehensive data on the incidence and mortality on a global scale. Objectives …

Objectives This article systematically reviews research on the costs of sepsis and, as a
secondary aim, evaluates the quality of economic evaluations reported in peer-reviewed …

Introduction Severe sepsis continues to be a significant burden on society. Methods Using
the International Classification of Diseases, Ninth Revision, Clinical Modification codes, we …

Importance The Early Management Bundle for Severe Sepsis/Septic Shock (SEP-1) is a
quality metric based on a care bundle for early sepsis management. Published evidence on …

Traditional methods for identifying pathogens in bacteremic patients are slow (24–48+ h).
This can lead to physicians making treatment decisions based on an incomplete diagnosis …

Introduction Administrative data are used to generate estimates of sepsis epidemiology and
can serve as source for quality indicators. Aim was to compare estimates on sepsis …

Background Although sepsis is the leading cause of death from infection, there are few
population-level epidemiological sepsis reports. The impact of sepsis-related deaths on all …

Sepsis is a clinical syndrome caused by a deregulated host response to an infection. Sepsis
is the most frequent cause of death in hospitalized patients. Although knowledge of the …