Obesity and COVID-19: molecular mechanisms linking both pandemics

A Ritter, NN Kreis, F Louwen, J Yuan - International journal of molecular …, 2020 - mdpi.com
The coronavirus disease 2019 COVID-19 pandemic is rapidly spreading worldwide and is
becoming a major public health crisis. Increasing evidence demonstrates a strong …

Nutritional therapy in persons suffering from psoriasis

J Garbicz, B Całyniuk, M Górski, M Buczkowska… - Nutrients, 2021 - mdpi.com
Psoriasis is a chronic inflammatory skin disease. Immunological, genetic, and environmental
factors, including diet, play a part in the pathogenesis of psoriasis. Metabolic syndrome or its …

Hypoxia-induced signaling in the cardiovascular system: pathogenesis and therapeutic targets

Y Zhao, W Xiong, C Li, R Zhao, H Lu, S Song… - … and Targeted Therapy, 2023 - nature.com
Hypoxia, characterized by reduced oxygen concentration, is a significant stressor that affects
the survival of aerobic species and plays a prominent role in cardiovascular diseases. From …

In search of new therapeutics—molecular aspects of the PCOS pathophysiology: genetics, hormones, metabolism and beyond

A Wawrzkiewicz-Jałowiecka, K Kowalczyk… - International Journal of …, 2020 - mdpi.com
In a healthy female reproductive system, a subtle hormonal and metabolic dance leads to
repetitive cyclic changes in the ovaries and uterus, which make an effective ovulation and …

DPP4 promotes human endothelial cell senescence and dysfunction via the PAR2–COX-2–TP axis and NLRP3 inflammasome activation

I Valencia, S Vallejo, P Dongil, A Romero… - …, 2022 - Am Heart Assoc
Background: Abnormal accumulation of senescent cells in the vessel wall leads to a
compromised vascular function contributing to vascular aging. Soluble DPP4 (dipeptidyl …

Adipokines in the Skin and in Dermatological Diseases

D Kovács, F Fazekas, A Oláh, D Törőcsik - International Journal of …, 2020 - mdpi.com
Adipokines are the primary mediators of adipose tissue-induced and regulated systemic
inflammatory diseases; however, recent findings revealed that serum levels of various …

Recent update on the molecular mechanisms of gonadal steroids action in adipose tissue

A Wawrzkiewicz-Jałowiecka, A Lalik… - International Journal of …, 2021 - mdpi.com
The gonadal steroids, including androgens, estrogens and progestogens, are involved in
the control of body fat distribution in humans. Nevertheless, not only the size and localization …

Use of antihyperglycemic drugs and risk of cancer in patients with diabetes

CS Søndergaard, PN Esquivel, M Dalamaga… - Current Oncology …, 2023 - Springer
Abstract Purpose of Review Diabetes is associated with an increased risk for several types
of cancer. Therefore, use of antihyperglycemic medications to lower blood glucose may …

Implication of diet and exercise on the management of age‐related sarcopenic obesity in Asians

YJ Kim, S Moon, JM Yu… - Geriatrics & Gerontology …, 2022 - Wiley Online Library
The incidence of sarcopenic obesity among adults aged≥ 65 years is rising worldwide.
Sarcopenic obesity is a high‐risk geriatric syndrome defined as a gain in the amount of …

[HTML][HTML] In an experimental myocardial infarction model, L-arginine pre-intervention may exert cardioprotective effects by regulating OTULIN levels and mitochondrial …

S Kaya, T Yalcın - Cell Stress and Chaperones, 2023 - Elsevier
The experimental myocardial infarction (MI) model originating from isoproterenol (ISO) is
frequently preferred in research due to its similarity to MI-induced damage in humans …