Ejaculation is a synchronized cascade of events that has the ultimate goal of activating
sperm and enabling them to reach an egg for fertilization. The seminal plasma contains a …

BACKGROUND The human sperm cell is very well suited for proteomic studies, as it is
accessible, can be easily purified and is believed to be transcriptionally and translationally …

After ejaculation, the mammalian male gamete must undergo the capacitation process,
which is a prerequisite for egg fertilization. The bioenergetics of sperm capacitation is poorly …

Physiology and metabolism are often sexually dimorphic, but the underlying mechanisms
remain incompletely understood. Here, we use the intestine of Drosophila melanogaster to …

The role of lipid metabolism has gained particular interest in prostate cancer research. A
large body of literature has outlined the unique upregulation of de novo lipid synthesis in …

Citrate, an organic trivalent anion, is a major substrate for generation of energy in most cells.
It is produced in mitochondria and used either in the Krebs' cycle or released into cytoplasm …

Although substantial evidence exists that sperm ATP production via glycolysis is required for
mammalian sperm function and male fertility, conflicting reports involving multiple species …

The citrate carrier (CIC) is an integral protein of the inner mitochondrial membrane which
catalyzes the efflux of mitochondrial citrate (or other tricarboxylates) in exchange with a …

Seminal plasma contains various types of extracellular vesicles, including 'prostasomes'.
Prostasomes are small vesicles secreted by prostatic epithelial cells that can be recruited by …

This work analysed intracellular calcium stores of boar spermatozoa subjected to 'in
vitro'capacitation (IVC) and subsequent progesterone‐induced acrosome exocytosis (IVAE) …