Sedentary behaviors (SB) are characterized by low energy expenditure while in a sitting or
reclining posture. Evidence relevant to understanding the physiology of SB can be derived …

Damage control resuscitation may lead to postoperative intra-abdominal hypertension or
abdominal compartment syndrome. These conditions may result in a vicious, self …

Humans are spending an increasing amount of time in space, where exposure to conditions
of microgravity causes 1–2% bone loss per month in astronauts. Through data collected …

Space is an extreme environment for the human body, where during long-term missions
microgravity and high radiation levels represent major threats to crew health. Intriguingly …

Venous thromboembolism (VTE) comprising deep venous thrombosis and pulmonary
embolism is a major cause of morbidity and mortality. Short-term immobility-related …

Long-duration bed rest is widely employed to simulate the effects of microgravity on various
physiological systems, especially for studies of bone, muscle, and the cardiovascular …

Key Points Astronauts have recently been discovered to have impaired vision, with a
presentation that resembles syndromes of elevated intracranial pressure on Earth. Gravity …

Prolonged periods of skeletal muscle inactivity or mechanical unloading (bed rest, hindlimb
unloading, immobilization, spaceflight and reduced step) can result in a significant loss of …

Whilst exposure to vibration is traditionally regarded as perilous, recent research has
focussed on potential benefits. Here, the physical principles of forced oscillations are …

It is not uncommon for people to spend one-half of their waking day sitting, with relatively
idle muscles. The other half of the day includes the often large volume of nonexercise …