Embryogenesis depends on a highly coordinated cascade of genetically encoded events. In
animals, maternal factors contributed by the egg cytoplasm initially control development …

Publisher Summary This chapter focuses on structure and expression of interleukin-6 (IL-6),
which is a cytokine with pleiotropic activities that plays a central role in host defense. IL-6 …

Organization of the genome into euchromatin and heterochromatin appears to be
evolutionarily conserved and relatively stable during lineage differentiation. In an effort to …

Abstract lNTERLEUKIN-6 (IL-6) is a multifunctional cytokine that regulates various aspects of
the immune response, acute-phase reaction and haematopoiesis (for reviews see refs 1, 2) …

Understanding preimplantation development is important both for basic reproductive biology
and for practical applications including regenerative medicine and livestock breeding …

A comprehensive analysis of transposable element (TE) expression in mammalian full-
grown oocytes reveals that LTR class III retrotransposons make an unexpectedly high …

Zygotic gene activation (ZGA) is the critical event that governs the transition from maternal to
embryonic control of development. In the mouse, ZGA occurs during the 2‐cell stage and …

How a more plastic chromatin state is maintained and reversed during development is
unknown. Heterochromatin-mediated silencing of repetitive elements occurs in differentiated …

The divergent homeobox gene Hex exhibits three notable expression patterns during early
mouse development. Initially Hex is expressed in the primitive endoderm of the implanting …

Recent advances in molecular technology and in vitro production of bovine embryos have
enabled studies of gene transcription in preimplantation embryos. On the basis of …