High-quality milk exosomes as oral drug delivery system

J Zhong, B Xia, S Shan, A Zheng, S Zhang, J Chen… - Biomaterials, 2021 - Elsevier
Many drugs must be administered intravenously instead of oral administration due to their
poor oral bioavailability. The cost of repeated infusion treatment for 6 weeks every year is as …

Exosome-derived microRNAs of human milk and their effects on infant health and development

BC Melnik, W Stremmel, R Weiskirchen, SM John… - Biomolecules, 2021 - mdpi.com
Multiple biologically active components of human milk support infant growth, health and
development. Milk provides a wide spectrum of mammary epithelial cell-derived …

Milk exosomes-mediated miR-31-5p delivery accelerates diabetic wound healing through promoting angiogenesis

C Yan, J Chen, C Wang, M Yuan, Y Kang, Z Wu… - Drug …, 2022 - Taylor & Francis
The refractory diabetic wound has remained a worldwide challenge as one of the major
health problems. The impaired angiogenesis phase during diabetic wound healing partly …

[HTML][HTML] Milk exosomes: Nature's abundant nanoplatform for theranostic applications

B Adriano, NM Cotto, N Chauhan, M Jaggi… - Bioactive materials, 2021 - Elsevier
Exosomes are a unique subpopulation of naturally occurring extracellular vesicles which are
smaller intracellular membrane nanoparticle vesicles. Exosomes have proven to be …

Exosomes as drug carriers in anti-cancer therapy

L Chen, L Wang, L Zhu, Z Xu, Y Liu, Z Li… - Frontiers in Cell and …, 2022 - frontiersin.org
Over the years, there has been a high demand for developing new safe and effective drug
carriers for cancer therapy. Emerging studies have indicated that exosomes can serve as …

The role of milk-derived exosomes in the treatment of diseases

M Rashidi, S Bijari, AH Khazaei… - Frontiers in …, 2022 - frontiersin.org
Exosomes (EXOs) are natural nanoparticles of endosome origin that are secreted by a
variety of cells in the body. Exosomes have been found in bio-fluids such as urine, saliva …

[HTML][HTML] Extracellular vesicles: the next generation theranostic nanomedicine for inflammatory bowel disease

D Li, M Yang, J Xu, H Xu, M Zhu, Y Liang… - International journal …, 2022 - ncbi.nlm.nih.gov
The recent rapid development in the field of extracellular vesicles (EVs) based
nanotechnology has provided unprecedented opportunities for nanomedicine platforms. As …

Hyaluronic acid-coated bovine milk exosomes for achieving tumor-specific intracellular delivery of miRNA-204

D Li, L Gong, H Lin, S Yao, Y Yin, Z Zhou, J Shi, Z Wu… - Cells, 2022 - mdpi.com
Cell type-specific drug delivery is a straightforward strategy to achieve targeted cancer
therapy and reduce side effects. Hyaluronic acid (HA), an US Food and Drug Administration …

Potential of colostrum-derived exosomes for promoting hair regeneration through the transition from telogen to anagen phase

H Kim, Y Jang, EH Kim, H Jang, H Cho… - Frontiers in Cell and …, 2022 - frontiersin.org
Human hair dermal papillary (DP) cells comprising mesenchymal stem cells in hair follicles
contribute critically to hair growth and cycle regulation. The transition of hair follicles from …

[HTML][HTML] The effectiveness of cell-derived exosome therapy for diabetic wound: A systematic review and meta-analysis

Z Qiao, X Wang, H Zhao, Y Deng, W Zeng… - Ageing Research …, 2023 - Elsevier
Background The prevalence of diabetes among the elderly population is significant and
rising annually. One of the most severe and frequent complications of diabetes mellitus is …