Background: Testicular germ cell tumours (TGCTs) are the most frequent tumour type among
young, adult men. TGCTs can be efficiently treated, but metastases of the teratoma subtype …

The ability of human pluripotent stem cells for unlimited proliferation and self-renewal
promotes their application in the fields of regenerative medicine. The morphological …

Human pluripotent stem cells are promising for a wide range of research and therapeutic
purposes. Their maintenance in culture requires the deep control of their pluripotent and …

Studies of monogenic diabetes are particularly useful because we can gain insight into the
molecular events of pancreatic β-cell failure. Maturity-onset diabetes of the young 1 …

Generating insulin-producing β-cells from human induced pluripotent stem cells is a
promising cell replacement therapy for improving or curing insulin-dependent diabetes. The …

Background Tandem mass tag spectrometry (TMT labeling-LC-MS/MS) was utilized to
examine the global proteomes of Atlantic halibut eggs at the 1-cell-stage post fertilization …

Background Induced pluripotent stem cells (iPS) can be generated from various somatic
cells and can subsequently be differentiated to multiple cell types of the body. This makes …

The application of patient-specific human induced pluripotent stem cells (hiPSCs) has a
great perspective for the development of personalized medicine. More than 10 hiPSCs …

The past decade revealed that cell identity changes, such as dedifferentiation or
transdifferentiation, accompany the insulin-producing β-cell decay in most diabetes …

Mesenchymal stem cells (MSC) have long been a cornerstone in bone tissue engineering
strategies, catalyzing the formation of new bone. Nevertheless, these cells generally present …