The exciting properties of micro-and nano-patterned surfaces found in natural species hide
a virtually endless potential of technological ideas, opening new opportunities for innovation …

Micro-and nanoscale structures produced on surfaces of metals, polymers, ceramics, and
glasses have many important applications in different fields such as engineering, medical …

The use of spinal implants for spine fusion has been steadily increasing to avoid the risks of
complications and donor site morbidity involved when using autologous bone. A variety of …

The stiffness and nanotopographical characteristics of the extracellular matrix (ECM)
influence numerous developmental, physiological, and pathological processes in vivo …

The current development of nanobiotechnologies requires a better understanding of cell–
surface interactions on the nanometre scale. Recently, advances in nanoscale patterning …

The interaction of mammalian cells with nanoscale topography has proven to be an
important signaling modality in controlling cell function. Naturally occurring nanotopographic …

The nanoscale surface topography of artificial materials is known to play a significant role in
interactions with biological systems such as proteins and cells. A detailed understanding …

As materials technology and the field of biomedical engineering advances, the role of
cellular mechanisms, in particular adhesive interactions with implantable devices, becomes …

Stem cells have the capacity to differentiate into various lineages, and the ability to reliably
direct stem cell fate determination would have tremendous potential for basic research and …

The ultimate goal in the design of biomimetic materials for use in tissue engineering as
permanent or resorbable tissue implants is to generate biocompatible scaffolds with …