[HTML][HTML] Environmental and genetic determinants of ankylosing spondylitis

R Bilski, P Kamiński, D Kupczyk, S Jeka… - International Journal of …, 2024 - mdpi.com
Exposure to heavy metals and lifestyle factors like smoking contribute to the production of
free oxygen radicals. This fact, combined with a lowered total antioxidant status, can induce …

Spondyloarthritis in North Africa: an update

S Slimani, W Hamdi, K Nassar, AA Kalla - Clinical Rheumatology, 2021 - Springer
Spondyloarthritis (SpA) has been less well studied than rheumatoid arthritis in North Africa,
due to a belief that it is rare and benign in certain populations. The main genetic trait of SpA …

What do we know about co-stimulatory and co-inhibitory immune checkpoint signals in ankylosing spondylitis?

C Schütz, X Baraliakos - Clinical and Experimental Immunology, 2023 - academic.oup.com
Ankylosing spondylitis is the main entity of a family of inflammatory diseases affecting many
musculoskeletal (sacroiliac joints, spine, and peripheral joints) and extra-musculoskeletal …

[HTML][HTML] Genetic biomarkers for diagnosis and treatment of spondyloarthropathies in Moroccan population

A Canossi, K Oumhani, T Del Beato, P Sebastiani… - Human Gene, 2024 - Elsevier
Abstract Background The spondyloarthropathies (SpA) are inflammatory rheumatologic
diseases whose pathogenesis comes from interaction between genetic and environmental …

Identification of susceptibility SNPs in CTLA-4 and PTPN22 for scleritis in Han Chinese

F Li, X Ma, L Du, L Shi, Q Cao, N Li… - Clinical & …, 2019 - academic.oup.com
The aim of this study was to determine the association between 13 single nucleotide
polymorphisms (SNPs) in the cytotoxic T lymphocyte-associated antigen-4 (CTLA4) and …

Characterization of ERAP1 rs30187 and rs10050860 polymorphisms and their association with ankylosing spondylitis in the Algerian population association of …

A Asmaa, B Ahmed, A Habiba, D Amira… - … Academic Journal of …, 2022 - journals.ekb.eg
Ankylosing spondylitis (AS) is chronic inflammatory rheumatism. The Endoplasmic
Reticulum Aminopeptidase (ERAP1) gene is considered the second genetic factor …

Features of Peripheral Blood Th-Cell Subset Composition and Serum Cytokine Level in Patients with Activity-Driven Ankylosing Spondylitis

PA Shesternya, AA Savchenko, OD Gritsenko… - Pharmaceuticals, 2022 - mdpi.com
Th cells may exhibit pathological activity depending on the regulatory and functional signals
sensed under a wide range of immunopathological conditions, including ankylosing …

Association study of copy number variants in CCL3L1, FCGR3A and FCGR3B genes with risk of ankylosing spondylitis in a West Algerian population

CA Dahmani, A Benzaoui, H Amroun… - International Journal …, 2019 - Wiley Online Library
Numerous single nucleotide polymorphisms (SNPs) were explored in the Algerian
population to evaluate associated ankylosing spondylitis (AS) genetic risk factors, but no …

Influencia genética en la variabilidad de la respuesta al tratamiento con Abatacept en pacientes con artritis reumatoide

N Márquez Pete - 2021 - digibug.ugr.es
La Artritis reumatoide (AR) es una enfermedad autoinmune crónica de etiología compleja
en la que interviene factores sociodemográficos, ambientales y genéticos, cuya prevalencia …

Role of regulatory T cells in pathogenesis and therapeutics of spondyloarthritis

M Harjacek - Regulatory T Cells and Autoimmune Diseases, 2024 - Elsevier
Spondyloarthritis (SpA) is an umbrella term for a group of chronic inflammatory disorders
that share common clinical and pathophysiological features characterized by enthesitis …