Abnormal placentation is considered as an underlying cause of various pregnancy
complications such as miscarriage, preeclampsia and intrauterine growth restriction, the …

During placentation invasive extravillous trophoblasts (EVTs) migrate into the maternal
uterus and modify its vessels. In particular, remodeling of the spiral arteries by EVTs is …

Defective placentation is the underlying cause of various pregnancy complications, such as
severe intrauterine growth restriction and preeclampsia. However, studies on human …

Embryo implantation involves the intimate interaction between an implantation-competent
blastocyst and a receptive uterus, which occurs in a limited time period known as the …

Background Despite evidence that genetic factors contribute to the duration of gestation and
the risk of preterm birth, robust associations with genetic variants have not been identified …

The placenta is a transient organ that forms during pregnancy to support the growth and
development of the fetus. During human placental development, trophoblast cells …

Wingless ligands, a family of secreted proteins, are critically involved in organ development
and tissue homeostasis by ensuring balanced rates of stem cell proliferation, cell death and …

Correct development of the human placenta and its differentiated epithelial cells, syncytial
trophoblasts (STBs) and extravillous trophoblasts (EVTs), is crucial for a successful …

The ovulatory menstrual cycle is the result of the integrated action of the hypothalamus,
pituitary, ovary, and endometrium. Like a metronome, the hypothalamus sets the beat for the …

The transformation of cytotrophoblast (CTB) to extravillous trophoblast (EVT) is an essential
process for placental implantation. EVT generated at the tips of the anchoring villi migrate …