[HTML][HTML] Diclofenac eco-geno-toxicity in freshwater algae, rotifers and crustaceans

C Russo, R Nugnes, E Orlo, A di Matteo… - Environmental …, 2023 - Elsevier
This study assessed the eco-genotoxic impact of diclofenac (DCF) in sentinel species of the
freshwater ecosystem. DCF residues are found in freshwater from few ng/L to tens of μg/L …

Biochemical alterations in diclofenac-treated rats: Effect of selenium on oxidative stress, inflammation, and hematological changes

SE Owumi, UJ Dim - Toxicology Research and Application, 2019 - journals.sagepub.com
We investigated the effect of selenium (Sel), a trace element in diclofenac sodium (DCF),
nonsteroidal anti-inflammatory drugs-induced hepatic and renal toxicities in adult rats. Five …

Ginger (Zingiber officinale) Root Capsules Enhance Analgesic and Antioxidant Efficacy of Diclofenac Sodium in Experimental Acute Inflammation

I Boarescu, RM Pop, PM Boarescu, IC Bocșan… - Antioxidants, 2023 - mdpi.com
Our study aimed to evaluate the analgesic and antioxidant effects of ginger (Zingiber
officinale) root capsule extract (GRCE) in addition to diclofenac (D) sodium treatment in …

α‐Lipoic acid alleviates dextran sulfate sodium salt‐induced ulcerative colitis via modulating the Keap1–Nrf2 signaling pathway and inhibiting ferroptosis

P Jiang, Z Zhai, L Zhao, K Zhang… - Journal of the Science of …, 2024 - Wiley Online Library
BACKGROUND Inflammatory bowel disease (IBD) is a chronically relapsing inflammatory
disease with severe diarrhea, fatigue and weight loss. α‐Lipoic acid (LA), a well‐known …

Confertin and scopoletin from leaf and root extracts of Hypochaeris radicata have anti-inflammatory and antioxidant activities

S Jamuna, K Karthika, S Paulsamy… - Industrial Crops and …, 2015 - Elsevier
Hypochaeris radicata is being prescribed by the local healers and Thoda tribals of Nilgiris,
the Western Ghats, India for the treatment of inflammation and various other ailments. This …

Curcumin Nanoparticles Enhance Antioxidant Efficacy of Diclofenac Sodium in Experimental Acute Inflammation

I Boarescu, PM Boarescu, RM Pop, IC Bocșan… - Biomedicines, 2021 - mdpi.com
We investigated the in vivo effect of curcumin nanoparticles (nC) in addition to diclofenac
sodium on local edema and oxidative stress parameters in carrageenan-induced paw …

[HTML][HTML] Mast cells and pro-inflammatory cytokines roles in assessment of grape seeds extract anti-inflammatory activity in rat model of carrageenan-induced paw …

AAM Abd-Allah, NAMN El-Deen… - Iranian journal of …, 2018 - ncbi.nlm.nih.gov
Objective (s): Reactive oxygen species (ROS)-produced oxidative disorders were involved
at the pathophysiology of many inflammatory processes via the generation of pro …

2-Hydroxybenzohydrazide as a novel potential candidate against nociception, inflammation, and pyrexia: in vitro, in vivo, and computational approaches

G Ali, NU Islam, M Qaim, R Ullah, MS Jan… - …, 2024 - Springer
The current study was designed to evaluate the 2-hydroxybenzohydrazide (HBH) as a drug
having efficacy against pyrexia, inflammation, and nociception. Besides, the therapeutic …

Pharmacological effect of a new idebenone formulation in a model of carrageenan-induced inflammatory pain

F Lauro, S Ilari, LA Giancotti, CA Ventura… - Pharmacological …, 2016 - Elsevier
Considerable evidence demonstrated that the central role of reactive oxygen species and
reactive nitrogen species (ROS and RNS) in the development of thermal hyperalgesia is …

Design and in vivo anti-inflammatory effect of ketoprofen delayed delivery systems

A Cerciello, G Auriemma, S Morello, A Pinto… - Journal of …, 2015 - Elsevier
For the treatment of inflammatory-based diseases affected by circadian rhythms, the
development of once-daily dosage forms is required to target early morning symptoms. In …