Sulfation is a dynamic and complex posttranslational modification process. It can occur at
various positions within the glycosaminoglycan (GAG) backbone and modulates …

Glycosaminoglycans (GAGs) are an important component of the extracellular matrix as they
influence cell behavior and have been sought for tissue regeneration, biomaterials, and …

To meet the growing need for tissue replacement materials for our aging population, the
development of new adaptive biomaterials is essential. The tissues with the highest demand …

The controlled fabrication of gradient materials is becoming increasingly important as the
next generation of tissue engineering seeks to produce inhomogeneous constructs with …

[Frontiers in Bioscience 17, 100-128, January 1, 2012] 100 Bone mineralization Ermanno
Bonucci1 Department of Experimental Medic Page 1 [Frontiers in Bioscience 17, 100-128 …

Proteoglycans are core proteins associated with carbohydrate/sugar moieties that are highly
variable in disaccharide composition, which dictates their function. These carbohydrates are …

Sulfated glycosaminoglycans (GAGs) can direct cellular processes by interacting with
proteins of the extracellular matrix (ECM). In this study we characterize the interaction …

Sulfated glycosaminoglycans (GAG) are multifunctional components of the extracellular
matrix and are involved in the regulation of adhesion, proliferation and differentiation of …

The bone microenvironment is a complex tissue in which heterogeneous cell populations of
hematopoietic and mesenchymal origin interact with environmental cues to maintain tissue …

The formation of lamellar bone in the soft tissues, where bone normally does not exist, is
called myositis ossificans. However, it would be more accurate to describe as myositis …