Human anti-IL-33 neutralizing monoclonal antibody

Y Fujino, T Yoshikawa, H Ochi - US Patent 9,758,578, 2017 - Google Patents
the present invention relates to a human anti-IL-33 neutralizing monoclonal antibody and an
antibody which competes therewith; and a cytokine expression inhibitor containing any of …

Antibodies directed against interleukin-33 (IL-33) and methods of making and using

RA Horlick, DJ King, AJ Mcknight - US Patent 10,059,764, 2018 - Google Patents
The invention relates to an isolated immunoglobulin heavy chain polypeptide and an
isolated immunoglobulin light chain polypeptide that bind to interleukin-33 (IL-33). The …

Vaccines with interleukin-33 as an adjuvant

D Weiner, D Villarreal, M Morrow, J Yan - US Patent 10,130,705, 2018 - Google Patents
Disclosed herein is a vaccine comprising an antigen and IL-33. Also disclosed herein is a
method for increasing an immune response in a subject in need thereof. Further disclosed …

Human anti-IL-33 neutralizing monoclonal antibody

Y Fujino, T Yoshikawa, H Ochi - US Patent 11,725,049, 2023 - Google Patents
An antibody has an antagonistic effect against IL-33. In particular an isolated human anti-IL-
33 neutralizing monoclonal antibody has framework regions with amino acid sequences …

Method of treating inflammatory disorder with antibodies directed against interleukin-33 (IL-33)

RA Horlick, DJ King, AJ Mcknight - US Patent 10,836,820, 2020 - Google Patents
8,841,417 B2 8,999,331 B2 9,090,694 B2 9,212,227 B2 9,382,318 B2 9,409,896 B2
9,447,183 B2 9,447,184 B2 9,453,072 B2 9,592,293 B2 9,611,307 B2 9,637,535 B2 …

Method of treating autoimmune disease with antibodies against IL-33

RA Horlick, DJ King, AJ Mcknight - US Patent 11,999,783, 2024 - Google Patents
The invention relates to an isolated immunoglobulin heavy chain polypeptide and an
isolated immunoglobulin light chain polypeptide that bind to interleukin-33 (IL-33). The …

IL-33 antagonist-containing therapeutic agent for endometriosis

T Yoshimoto, JM Palumbo, VI Stone, T Kato… - US Patent …, 2022 - Google Patents
Based on the identification of IL-33 as an exacerbating factor in endometriosis and
adenomyosis uteri, a therapeutic agent for endometriosis and adenomyosis uteri has an IL …

DNA molecules encoding anti-IL-33 antibodies

RJ Benschop, J Davies, AJ Okragly, CN Patel… - US Patent …, 2021 - Google Patents
US10913793B2 - DNA molecules encoding anti-IL-33 antibodies - Google Patents
US10913793B2 - DNA molecules encoding anti-IL-33 antibodies - Google Patents DNA …

Vaccines with interleukin-33 as an adjuvant

D Weiner, D Villarreal, M Morrow, J Yan - US Patent 10,933,130, 2021 - Google Patents
Disclosed herein is a vaccine comprising an antigen and IL-33. Also disclosed herein is a
method for increasing an immune response in a subject in need thereof. Further disclosed …

Anti-IL-33 antibodies and uses thereof for disease treatment

RJ Benschop, J Davies, AJ Okragly, CN Patel… - US Patent …, 2019 - Google Patents
US10501536B2 - Anti-IL-33 antibodies and uses thereof for disease treatment - Google
Patents US10501536B2 - Anti-IL-33 antibodies and uses thereof for disease treatment …