Endothelial cells (ECs) are more than inert blood vessel lining material. Instead, they are
active players in the formation of new blood vessels (angiogenesis) both in health and (life …

Background A growing number of studies linked elevated concentrations of circulating
asymmetric (ADMA) and symmetric (SDMA) dimethylarginine to mortality and cardiovascular …

Asymmetric dimethylarginine (ADMA) and its enantiomer, Symmetric dimethylarginine
(SDMA), are naturally occurring amino acids that were first isolated and characterized in …

Cardiovascular disease (CV) is the most common cause of premature mortality in patients
with rheumatoid arthritis (RA). This is the result of an accelerated atherosclerotic process …

Background Asymmetric dimethylarginine (ADMA) inhibits the production of nitric oxide, a
key regulator of the vascular tone, and may be important in the development of …

The impact of statin therapy on plasma asymmetric dimethylarginine (ADMA) levels has not
been conclusively studied. Therefore the aim of the meta-analysis was to assess the effect of …

Here we evaluated the performance of a large set of serum biomarkers for the prediction of
rapid progression of chronic kidney disease (CKD) in patients with type 2 diabetes. We used …

Low plasma levels of high-density lipoprotein (HDL) cholesterol are associated with
increased risks of coronary heart disease. HDL mediates cholesterol efflux from …

Atherosclerosis is a leading cause of morbidity and mortality in Western society. Despite
improved insight into disease pathogenesis and therapeutic options, additional treatment …

Background Chronic kidney disease (CKD) is associated with increased risk of renal and
cardiovascular events. It has been claimed that endogenous methylarginines, asymmetric …