Characterization of the function of Adenovirus L4 gene products and their impact on AAV vector production

Y Nie, H Pan, Q Li, H Na, B Figueroa… - … Therapy Methods & …, 2024 - cell.com
Efficient manufacturing of recombinant adenovirus-associated virus (AAV) vectors is critical
to the successful development of genomic medicines. We attempted to optimize AAV vector …

E1B-55K is a phosphorylation-dependent transcriptional and posttranscriptional regulator of viral gene expression in human adenovirus C5 infection

P Hidalgo, Y Garcés, E Mundo, RE López… - Journal of …, 2022 - Am Soc Microbiol
The multifunctional adenoviral E1B-55K phosphoprotein is a major regulator of viral
replication and plays key roles in virus-mediated cell transformation. While much is known …

E2A, VA RNA I, and L4-22k adenoviral helper genes are sufficient for AAV production in HEK293 cells

J Doshi, E Couto, J Staiti, LH Vandenberghe… - … Therapy Methods & …, 2024 - cell.com
The replication-defective adeno-associated virus (AAV) is extensively utilized as a research
tool or vector for gene therapy. The production process of AAV remains intricate, expensive …

[PDF][PDF] 鸭腺病毒3 型MGB TaqMan 探针实时荧光定量PCR 检测方法的建立

陈翠腾, 陈珍, 朱春华, 蔡国漳, 刘斌琼… - 农业生物技术 …, 2019 - journal05.magtech.org.cn
摘要鸭(Anas platyrhynchos domestica) 腺病毒3 型(Duck adenovirus type 3, DAdV-3)
是近年来我国新发现的鸭源腺病毒. 本研究根据NCBI 数据库中DAdV-3 代表株(CH-GD-12 …

Development of a self-silencing adenovirus for the efficient manufacture of adeno-associated virus vectors

W Su - 2021 - ora.ox.ac.uk
Adeno-associated virus (AAV) shows great promise for gene therapy, however scalability,
yield and quality remain significant issues. The most common 'helper-free'method used to …

[PDF][PDF] Detection and Partial Nucleotide Sequence of Egg Drop Syndrome Virus from a Poultry Flock in Ogun State, Nigeria

MA Ockiya, TA Jarikre, AT Jibril, CAO Adeyefa - pcujournals.org.ng
This study investigated Egg Drop Syndrome (EDS) on a poultry farm at Ayepe Road,
Shagamu, Ogun State, Nigeria using clinical, serological and molecular methods. Samples …

[图书][B] Ribosome Profiling of Late Adenovirus Infected Cells Reveals Ribosome Stacking on the 5′ Untranslated Region of Late Messenger RNA

JM Gagliano - 2019 - search.proquest.com
Adenovirus type 5 is a non-enveloped, icosahedral capsid, containing a linear genome thirty-
five thousand base-pairs in length. The genome has 16 genes that, through alternative …

Human adenovirus–host cell interplay: The role of the cellular zinc finger proteins and mitochondrial DNA

K Mun - 2019 - diva-portal.org
Human adenovirus – host cell interplay : The role of the cellular zinc finger proteins and
mitochondrial DNA diva-portal.org Digitala Vetenskapliga Arkivet Simple search Advanced …

Functional characterization of the human adenovirus pVII protein and non-coding VA RNAI

R Inturi - 2017 - diva-portal.org
Abstract Inturi, R. 2017. Functional characterization of the human adenovirus pVII protein
and non-coding VA RNAI. Digital Comprehensive Summaries of Uppsala Dissertations from …