Biologics or Janus Kinase Inhibitors in Rheumatoid Arthritis Patients Who are Insufficient Responders to Conventional Anti-Rheumatic Drugs

EG Favalli, G Maioli, R Caporali - Drugs, 2024 - Springer
Rheumatoid arthritis (RA) is a chronic immune-mediated inflammatory disease which can
induce progressive disability if not properly treated early. Over the last 20 years, the …

Real-world effectiveness of biological therapy in patients with rheumatoid arthritis: Systematic review and meta-analysis

CT Castro, MJ Queiroz, FC Albuquerque… - Frontiers in …, 2022 - frontiersin.org
Background: The treatment of rheumatoid arthritis (RA), a chronic systemic inflammatory
autoimmune disease, is based on disease-modifying anti-rheumatic drugs (DMARDs) …

Therapeutic equivalence of biosimilar and reference biologic drugs in rheumatoid arthritis: A systematic review and meta-analysis

B de Oliveira Ascef, MO Almeida… - JAMA Network …, 2023 - jamanetwork.com
Importance Biosimilar drugs are potentially lower-cost versions of biologics that may
improve access to therapy. However, there is a lack of adequate systematic reviews …

Changes in the use patterns of bDMARDs in patients with rheumatic diseases over the past 13 years

C Sánchez-Piedra, D Sueiro-Delgado… - Scientific Reports, 2021 - nature.com
The better understanding of the safety of biologic DMARDs (bDMARDs), as well as the
emergence of new bDMARDs against different therapeutic targets and biosimilars have …

Managing inadequate response to initial anti-TNF therapy in rheumatoid arthritis: optimising treatment outcomes

PC Taylor, M Matucci Cerinic, R Alten… - Therapeutic …, 2022 - journals.sagepub.com
Anti-tumour necrosis factors (anti-TNFs) are established as first-line biological therapy for
rheumatoid arthritis (RA) with over two decades of accumulated clinical experience. Anti …

Abatacept in rheumatoid arthritis: survival on drug, clinical outcomes, and their predictors—data from a large national quality register

G Cagnotto, M Willim, JÅ Nilsson, M Compagno… - Arthritis research & …, 2020 - Springer
Background There are limited data regarding efficacy of abatacept treatment for rheumatoid
arthritis (RA) outside clinical trials. Quality registers have been useful for observational …

One year in review 2019: novelties in the treatment of rheumatoid arthritis

E Silvagni, M Di Battista, A Bonifacio… - Clinical and …, 2019 - boa.unimib.it
The current treatment approach in rheumatoid arthritis (RA) follows a stepwise management,
starting from early introduction of conventional synthetic (cs) disease-modifying anti …

Efficacy and safety of subcutaneous infliximab versus adalimumab, etanercept and intravenous infliximab in patients with rheumatoid arthritis: a systematic literature …

R Caporali, Y Allanore, R Alten, B Combe… - Expert review of …, 2021 - Taylor & Francis
Objectives There are few comparative data for tumor necrosis factor inhibitors in patients
with rheumatoid arthritis (RA). Methods Historical data for reference product/biosimilar …

Switching and discontinuation pattern of biologic disease-modifying antirheumatic drugs and tofacitinib for patients with rheumatoid arthritis in Taiwan

KJ Li, CL Chang, CY Hsin, CH Tang - Frontiers in Pharmacology, 2021 - frontiersin.org
Rheumatoid arthritis (RA) is a chronic inflammatory systemic disease characterized by
persistent joint synovial inflammation and swelling, leading to cartilage damage and bone …

Risk of hospitalization for heart failure in rheumatoid arthritis patients treated with etanercept and abatacept

E Generali, G Carrara, M Kallikourdis… - Rheumatology …, 2019 - Springer
To estimate biologic influence on heart failure (HF) risk in rheumatoid arthritis. Retrospective
cohort (RECORD Study of Italian Society for Rheumatology) study on administrative …