Anesthesia and cancer, friend or foe? A narrative review

J Montejano, V Jevtovic-Todorovic - Frontiers in Oncology, 2021 - frontiersin.org
Cancer remains the leading cause of death worldwide with close to 10 million deaths
reported annually. Due to growth of the advanced age cohort in our population, it is …

Chronic cancer pain: opioids within tumor microenvironment affect neuroinflammation, tumor and pain evolution

A Santoni, M Santoni, E Arcuri - Cancers, 2022 - mdpi.com
Simple Summary Pain is a worrisome symptom that 60–80% of patients with cancer
experience chronically. In the last twenty years, immunological and pain research have …

[HTML][HTML] Comparison between epidural and intravenous analgesia effects on disease-free survival after colorectal cancer surgery: a randomised multicentre controlled …

W Falk, A Magnuson, C Eintrei, R Henningsson… - British Journal of …, 2021 - Elsevier
Background Thoracic epidural analgesia (TEA) has been suggested to improve survival
after curative surgery for colorectal cancer compared with systemic opioid analgesia. The …

Sodium channels and the ionic microenvironment of breast tumours

TK Leslie, WJ Brackenbury - The Journal of Physiology, 2023 - Wiley Online Library
Cancers of epithelial origin such as breast, prostate, cervical, gastric, colon and lung cancer
account for a large proportion of deaths worldwide. Better treatment of metastasis, the main …

[HTML][HTML] Inhalation or total intravenous anaesthesia and recurrence after colorectal cancer surgery: a propensity score matched Danish registry-based study

RP Hasselager, J Hallas, I Gögenur - British journal of anaesthesia, 2021 - Elsevier
Background During colorectal cancer surgery, the immune-modulating effects of inhalation
anaesthesia may create a favourable environment for metastasis formation, leading to …

Lidocaine inhibits the metastatic potential of ovarian cancer by blocking NaV1.5‐mediated EMT and FAK/Paxillin signaling pathway

C Liu, M Yu, Y Li, H Wang, C Xu, X Zhang… - Cancer …, 2021 - Wiley Online Library
Lidocaine, one of the most commonly used local anesthetics during surgery, has been
reported to suppress cancer cell growth via blocking voltage‐gated sodium channels …

Epidural analgesia and recurrence after colorectal cancer surgery: a Danish retrospective registry-based cohort study

RP Hasselager, J Hallas, I Gögenur - Anesthesiology, 2022 - ingentaconnect.com
Background: Surgery is the main curative treatment for colorectal cancer. Yet the
immunologic and humoral response to surgery may facilitate progression of micro …

Pharmacological and nutritional targeting of voltage-gated sodium channels in the treatment of cancers

O Lopez-Charcas, P Pukkanasut, SE Velu… - IScience, 2021 - cell.com
Voltage-gated sodium (Na V) channels, initially characterized in excitable cells, have been
shown to be aberrantly expressed in non-excitable cancer tissues and cells from epithelial …

Opioid-free anesthesia and postoperative outcomes in cancer surgery: a systematic review

D Bugada, M Drotar, S Finazzi, G Real, LF Lorini… - Cancers, 2022 - mdpi.com
Simple Summary As a significant knowledge gap exists on the effect of opioid-free
anesthesia on outcomes of cancer patients receiving surgery, we conducted a systematic …

Effect of volatile anesthetics on myocardial infarction after coronary artery surgery: a post hoc analysis of a randomized trial

A Zangrillo, VV Lomivorotov, VV Pasyuga… - Journal of cardiothoracic …, 2022 - Elsevier
Objective To investigate the effect of volatile anesthetics on the rates of postoperative
myocardial infarction (MI) and cardiac death after coronary artery bypass graft (CABG) …