Sponges (phylum Porifera) are sessile marine filter feeders that have developed efficient
defense mechanisms against foreign attackers such as viruses, bacteria, or eukaryotic …

Covering: 2005. Previous review: Nat. Prod. Rep., 2006, 23, 26 This review covers the
literature published in 2005 for marine natural products, with 704 citations (493 for the …

The goal of this review is to highlight the wide range of biological activities displayed by
purines, with particular emphasis on new purine-based agents which find potential …

Covering: 2003–2005. Previous review: Nat. Prod. Rep., 2003, 20, 535–557 This review
covers natural products (secondary metabolites) with reported growth inhibitory activity …

Tuberculosis has been one of the greatest global health challenges of all time. Although the
current first-line anti-tuberculosis (anti-TB) medicines used in the clinic have reduced …

An increasing incidence of deaths due to tuberculosis and the known drawbacks of the
current existing drugs including the emergence of multi drug-resistant strains have led to a …

Despite of the advances made in the treatment and management, tuberculosis (TB) still
remains one of main public health problem. The contrary effects of first and second-line anti …

Agelasine and agelasimine derivatives with substantially less complicated terpenoid side
chains compared to the naturally occurring compounds have been synthesized and their …

A number of 6-(2-furyl)-9-(p-methoxybenzyl) purines carrying a variety of substituents in the
2-or 8-position have been synthesized and their ability to inhibit growth of Mycobacterium …

Three new N-methyladenine-containing diterpenes, 2-oxoagelasines A (1) and F (2) and 10-
hydro-9-hydroxyagelasine F (3), were isolated from the Okinawan marine sponge Agelas …