Advances in the microbiological diagnosis of prosthetic joint infections

ME Portillo, I Sancho - Diagnostics, 2023 - mdpi.com
A significant number of prosthetic joint infections (PJI) are culture-negative and/or
misinterpreted as aseptic failures in spite of the correct implementation of diagnostic culture …

Review of calcium-sulphate-based ceramics and synthetic bone substitutes used for antibiotic delivery in PJI and osteomyelitis treatment

R Ene, M Nica, D Ene, A Cursaru… - EFORT open …, 2021 - eor.bioscientifica.com
Infection in orthopaedic and trauma surgery remains a destructive complication with
particularly challenging diagnosis and treatment due to bacterial antibiotic resistance and …

Success rates of debridement, antibiotics, and implant retention in 230 infected total knee arthroplasties: implications for classification of periprosthetic joint infection

MF Zhu, K Kim, A Cavadino, B Coleman… - The Journal of …, 2021 - Elsevier
Background Prosthetic joint infection (PJI) is the most common cause of failure following
total knee arthroplasty (TKA). This study aimed to determine the success of debridement …

Predictors of treatment success after periprosthetic joint infection: 24-month follow up from a multicenter prospective observational cohort study of 653 patients

JS Davis, S Metcalf, B Clark… - Open Forum …, 2022 - academic.oup.com
Background Periprosthetic joint infection (PJI) is a devastating condition and there is a lack
of evidence to guide its management. We hypothesized that treatment success is …

Antimicrobial treatment of patients with a periprosthetic joint infection: basic principles

W Rottier, J Seidelman, M Wouthuyzen-Bakker - Arthroplasty, 2023 - Springer
The antibiotic treatment of periprosthetic joint infections (PJI) is complicated by the presence
of biofilm produced by bacteria on the abiotic surface of the implant. Bacteria within the …

Enough is enough: salvage procedures in severe periprosthetic joint infection

Y Gramlich, J Parvizi - Arthroplasty, 2023 - Springer
Background In severe cases of periprosthetic joint infection involving negative host-
dependent factors, individual-based decisions between a curative therapy vs. salvage …

Debridement, antibiotics, and implant retention after revision arthroplasty: antibiotic mismatch, timing, and repeated DAIR associated with poor outcome

K Veerman, J Raessens, D Telgt… - The Bone & Joint …, 2022 - boneandjoint.org.uk
Aims Debridement, antibiotics, and implant retention (DAIR) is a widely accepted form of
surgical treatment for patients with an early periprosthetic joint infection (PJI) after primary …

Principles of mechanical and chemical debridement with implant retention

DG Deckey, ZK Christopher, JS Bingham, MJ Spangehl - Arthroplasty, 2023 - Springer
Background Periprosthetic joint infection (PJI) is one of the most common causes of early
revision for total hip and knee arthroplasty. Mechanical and chemical debridement typically …

Lower success rate of débridement and implant retention in late acute versus early acute periprosthetic joint infection caused by Staphylococcus spp. results from a …

M Wouthuyzen-Bakker, M Sebillotte… - Clinical Orthopaedics …, 2020 - journals.lww.com
Background Surgical débridement, antibiotics and implant retention (DAIR) is currently
recommended by international guidelines for both early acute (postsurgical) and late acute …

The AAHKS best podium presentation research award: comparing the efficacy of irrigation solutions on staphylococcal biofilm formed on arthroplasty surfaces

A Premkumar, SN Nishtala, JT Nguyen… - The Journal of …, 2021 - Elsevier
Background A diverse array of antibacterial solutions is utilized by orthopedic surgeons in
an attempt to disperse bacterial biofilm. Few studies compare these agents against biofilm …