EBV was the first human virus to be directly implicated in carcinogenesis. It infects> 90% of
the world's population. Although most humans coexist with the virus without serious …

Abstract In vitro, Epstein-Barr virus (EBV) will infect any resting B cell, driving it out of the
resting state to become an activated proliferating lymphoblast. Paradoxically, EBV persists in …

With current techniques, genetic alterations of herpesviruses are difficult to perform, mostly
because of the large size of their genomes. To solve this problem, we have designed a …

The Epstein–Barr virus (EBV) latent membrane protein 1 (LMP1) is essential for the
immortalization of human B cells and is linked etiologically to several human tumors. LMP1 …

Vaccination provides a powerful means to control infections. It exploits and exemplifies the
ability of the immune system to preserve the information that a specific pathogen has been …

Abstract Latent membrane protein 1 (LMP1) of Epstein–Barr virus (EBV) is an integral
membrane protein which has transforming potential and is necessary but not sufficient for B …

CD40 is a cell surface receptor that belongs to the tumor necrosis factor receptor family. It
was first identified and functionally characterized on B lymphocytes; however, in recent …

Epstein–Barr virus is a tumorigenic herpes virus that is ubiquitous in the adult population.
The virus is generally spread to and between young children through salivary contact, and …

Epstein-Barr virus (EBV) infects and transforms primary B lymphocytes in vitro. Viral infection
initiates the cell cycle entry of the resting B lymphocytes. The maintenance of proliferation in …

Almost exactly twenty years after the discovery of Epstein-Barr virus (EBV), the latent
membrane protein 1 (LMP1) entered the EBV stage, and soon thereafter, it was recognized …