Warfarin is an anticoagulant commonly used as an oral drug in preventing and treating
thromboembolic diseases. The international normalized ratio (INR) is a clinical monitoring …

Background: Vitamin K antagonists (VKAs) are class I oral anticoagulants that are widely
prescribed following surgical heart valve implantation. The objective of this study was to …

Aims Warfarin dose requirement varies significantly. We compared the clinically established
doses based on international normalized ratio (INR) among patients with severe thrombosis …

The aim of the study: to establish the frequencies of polymorphisms in VKORC1, CYP2C9
and CYP4F2 genes among residents of the Zaporizhzhia region. Materials and methods. A …

Để hoàn thành luận án này, trước hết, tôi xin bày tỏ lòng tri ân sâu sắc tới GS. TS. Tạ Thành
Văn, Chủ tịch Hội đồng Trường, Nguyên Hiệu trưởng, Trưởng Bộ môn Hóa sinh Trường Đại …

Background: Warfarin is primarily metabolized by cytochrome P450 2C9 (CYP2C9) enzyme,
which is encoded by the CYP2C9 gene. CYP2C9* 2 and CYP2C9* 3 variants significantly …

Дисертація присвячена прогнозуванню безпечності та оптимізації антикоагулянтної
терапії при фібриляції передсердь (ФП) шляхом дослідження клінічних особливостей …

Background: Warfarin is the most commonly prescribed anticoagulant drug for treating
thromboembolic events. There is a variation in dose requirements for each individual due to …

Цель исследования–изучить и проанализировать вклад в частоту развития
кровотечений–носительства полиморфизмов, влияющих на метаболизм варфарина–c …

Background: To evaluate the accuracy and predictive performance of multiple linear
regression algorithms, Gage algorithm and International Warfarin Pharmacogenetics …