The endoplasmic reticulum (ER) plays a critical role in the synthesis and chaperoning of
membrane-associated and secreted proteins. The membrane is also an important site of …

While N‐glycan synthesis in the endoplasmic reticulum (ER) is relatively well conserved in
eukaryotes, N‐glycan processing and O‐glycan biosynthesis in the Golgi apparatus are …

N-glycosylation is a major modification of proteins in plant cells. This process starts in the
endoplasmic reticulum by the co-translational transfer of a precursor oligosaccharide to …

The functions of plant glycoside hydrolases and transglycosidases have been studied using
different biochemical and molecular genetic approaches. These enzymes are involved in the …

There are major structural differences between plant and mammalian N-linked glycans, with
those from plants being immunogenic in most laboratory mammals and eliciting glycan …

In plants, most proteins of the extracellular compartment and the endomembrane system are
glycosylated by N-linked oligosaccharides. The N-glycosylation of proteins has a great …

Asparagine (N)-linked protein glycosylation is one of the most crucial, prevalent, and
complex co-and post-translational protein modifications. It plays a pivotal role in protein …

Antibodies have long been recognized for their diagnostic and therapeutic potential. The
rapidly increasing number of monoclonal antibodies approved for immunotherapy has …

Plant‐based expression systems are attractive for the large‐scale production of
pharmaceutical proteins. However, glycoproteins require particular attention as inherent …

Plant-specific glycosylation has long been a major limitation to the extensive use of plant-
made pharmaceuticals in human therapy. Our goal here is to highlight the progress recently …