New fundamentals in hemostasis

HH Versteeg, JWM Heemskerk, M Levi… - Physiological …, 2013 - journals.physiology.org
Hemostasis encompasses the tightly regulated processes of blood clotting, platelet
activation, and vascular repair. After wounding, the hemostatic system engages a plethora of …

Microvesicles in vascular homeostasis and diseases

VC Ridger, CM Boulanger… - Thrombosis and …, 2017 - thieme-connect.com
Microvesicles are members of the family of extracellular vesicles shed from the plasma
membrane of activated or apoptotic cells. Microvesicles were initially characterised by their …

Intratumoral immunotherapy using platelet-cloaked nanoparticles enhances antitumor immunity in solid tumors

B Bahmani, H Gong, BT Luk, KJ Haushalter… - Nature …, 2021 - nature.com
Intratumoral immunotherapy is an emerging modality for the treatment of solid tumors. Toll-
like receptor (TLR) agonists have shown promise for eliciting immune responses, but …

Platelet-derived microvesicles in cardiovascular diseases

MTK Zaldivia, JD McFadyen, B Lim, X Wang… - Frontiers in …, 2017 - frontiersin.org
Microvesicles (MVs) circulating in the blood are small vesicles (100–1,000 nm in diameter)
derived from membrane blebs of cells such as activated platelets, endothelial cells, and …

Role of platelet-derived microvesicles as crosstalk mediators in atherothrombosis and future pharmacology targets: a link between inflammation, atherosclerosis, and …

L Badimon, R Suades, E Fuentes, I Palomo… - Frontiers in …, 2016 - frontiersin.org
Reports in the last decade have suggested that the role of platelets in atherosclerosis and its
thrombotic complications may be mediated, in part, by local secretion of platelet-derived …

Effects of an acute bout of exercise on circulating extracellular vesicles: tissue-, sex-, and BMI-related differences

AE Rigamonti, V Bollati, L Pergoli, S Iodice… - International Journal of …, 2020 - nature.com
Background Exercise is recognized to evoke multisystemic adaptations that, particularly in
obese subjects, reduce body weight, improve glucometabolic control, counteract …

[HTML][HTML] Exosomes: An emerging factor in atherosclerosis

Y Wang, Y Xie, A Zhang, M Wang, Z Fang… - Biomedicine & …, 2019 - Elsevier
Atherosclerosis is the main reason for morbidity and death caused by cardiovascular
disease which leads to approximately 20% of total death around the world. Exosomes …

Initiation and propagation of vascular calcification is regulated by a concert of platelet-and smooth muscle cell-derived extracellular vesicles

LJ Schurgers, AC Akbulut, DM Kaczor… - Frontiers in …, 2018 - frontiersin.org
The ageing population continues to suffer from its primary killer, cardiovascular disease
(CVD). Despite recent advances in interventional medicinal and surgical therapies towards …

Extracellular vesicles as drivers of immunoinflammation in atherothrombosis

R Suades, MF Greco, T Padró, L Badimon - Cells, 2022 - mdpi.com
Atherosclerotic cardiovascular disease is the leading cause of morbidity and mortality all
over the world. Extracellular vesicles (EVs), small lipid-bilayer membrane vesicles released …

Multifaceted role of extracellular vesicles in atherosclerosis

A Konkoth, R Saraswat, C Dubrou, F Sabatier… - Atherosclerosis, 2021 - Elsevier
Extracellular vesicles (EVs) are small vesicles released by the majority of cells in response
to cell activation or death stimuli. They are grouped as small EVs or exosomes, large EVs …