Crohn's disease is a chronic inflammatory bowel disease of unknown cause, affecting
approximately 1.4 million North American people. Due to the similarities between Crohn's …

The acute-phase response is triggered by the presence of infectious agents and danger
signals which indicate hazards for the integrity of the mammalian body. One central feature …

Sufficient mineral supply is vital not only for the innate immune system but also for the
components of the adaptive immune defense, which encompass defense mechanisms …

Iron is essential for many biological processes, however, too much or too little iron can result
in a wide variety of pathological consequences, depending on the organ system, tissue or …

Tuberculosis (TB) is a persistent global pandemic, and standard treatment for it has not
changed for 30 years. Mycobacterium tuberculosis (Mtb) has undergone prolonged …

Immunoglobulin genes are rarely considered as disease susceptibility genes despite their
obvious and central contributions to immune function. This appears to be a consequence of …

Diabetes, a leading cause of death globally, has different types, with Type 2 Diabetes
Mellitus (T2DM) being the most prevalent one. It has been established that variations in the …

Paratuberculosis, or Johne's Disease (JD) is a debilitating chronic enteritis mainly affecting
ruminants caused by Mycobacterium avium subsp. paratuberculosis (MAP). This organism …

Transcriptome arrays identifies 747 genes differentially expressed in the anterior horn of the
spinal cord and 2,300 genes differentially expressed in frontal cortex area 8 in a single …

Ingesting probiotics contributes to the development of a healthy microflora in the GIT with
established benefits to human health. Some of these beneficial effects may be through the …