Flavonoids as natural phenolic compounds and their role in therapeutics: An overview

RE Mutha, AU Tatiya, SJ Surana - Future journal of pharmaceutical …, 2021 - Springer
Background Natural plants and plant-derived formulations have been used by mankind from
the ancient period of time. For the past few years, many investigations elaborated the …

A review of the anti-inflammatory effects of rosmarinic acid on inflammatory diseases

C Luo, L Zou, H Sun, J Peng, C Gao, L Bao… - Frontiers in …, 2020 - frontiersin.org
Inflammatory diseases are caused by abnormal immune responses and are characterized
by an imbalance of inflammatory mediators and cells. In recent years, the anti-inflammatory …

Therapeutic potential of rosmarinic acid: A comprehensive review

M Nadeem, M Imran, T Aslam Gondal, A Imran… - Applied Sciences, 2019 - mdpi.com
Naturally occurring food-derived active ingredients have received huge attention for their
chemopreventive and chemotherapy capabilities in several diseases. Rosmarinic acid (RA) …

Anxiolytic and antidepressive potentials of rosmarinic acid: A review with a focus on antioxidant and anti-inflammatory effects

A Dahchour - Pharmacological Research, 2022 - Elsevier
Depression and anxiety are the most prevalent neuropsychiatric disorders that have
emerged as global health concerns. Anxiolytic and antidepressant drugs, such as …

Rosmarinic acid–pharmaceutical and clinical aspects

SKS Amoah, LP Sandjo, JM Kratz, MW Biavatti - Planta medica, 2016 - thieme-connect.com
The biosynthesis and biotechnological production of Rosmarinic acid, a phenolic ester that
is widespread in the plant kingdom, has been widely investigated. This compound has …

[HTML][HTML] Zingerone ameliorates cisplatin‐induced ovarian and uterine toxicity via suppression of sex hormone imbalances, oxidative stress, inflammation and …

C Caglayan, FM Kandemir, S Yıldırım… - Biomedicine & …, 2018 - Elsevier
Cisplatin (CP) is a widely used chemotherapeutic drug, effective against a variety of solid
tumours, though its utility is limited due to its multiple organ toxicity. Zingerone (ZO), one of …

The role of inflammation in cadmium nephrotoxicity: NF-κB comes into view

EHM Hassanein, WR Mohamed, OS Ahmed… - Life Sciences, 2022 - Elsevier
Kidney diseases are major health problem and understanding the underlined mechanisms
that lead to kidney diseases are critical research points with a marked potential impact on …

[HTML][HTML] Hepatoprotective effects of rosmarinic acid: Insight into its mechanisms of action

TO Elufioye, S Habtemariam - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Liver diseases such as hepatitis, fibrosis, cirrhosis, and hepatocellular carcinoma are one of
the major health challenges in the world and many conditions such as inadequate nutrition …

Ginsenoside Rg5 ameliorates cisplatin-induced nephrotoxicity in mice through inhibition of inflammation, oxidative stress, and apoptosis

W Li, MH Yan, Y Liu, Z Liu, Z Wang, C Chen, J Zhang… - Nutrients, 2016 - mdpi.com
Although cisplatin is an effective anti-cancer agent that is widely used for treating various
types of malignant solid tumors, the nephrotoxicity induced by cisplatin severely limits its …

Antioxidant supplementation in the treatment of neurotoxicity induced by platinum-based chemotherapeutics—a review

JSK Stankovic, D Selakovic, V Mihailovic… - International Journal of …, 2020 - mdpi.com
Cancer represents one of the most pernicious public health problems with a high mortality
rate among patients worldwide. Chemotherapy is one of the major therapeutic approaches …