Immunological mechanisms of vaccine-induced protection against COVID-19 in humans
M Sadarangani, A Marchant… - Nature Reviews …, 2021 - nature.com
Most COVID-19 vaccines are designed to elicit immune responses, ideally neutralizing
antibodies (NAbs), against the SARS-CoV-2 spike protein. Several vaccines, including …
antibodies (NAbs), against the SARS-CoV-2 spike protein. Several vaccines, including …
The current landscape of nucleic acid therapeutics
The increasing number of approved nucleic acid therapeutics demonstrates the potential to
treat diseases by targeting their genetic blueprints in vivo. Conventional treatments …
treat diseases by targeting their genetic blueprints in vivo. Conventional treatments …
The evolution of commercial drug delivery technologies
Drug delivery technologies have enabled the development of many pharmaceutical
products that improve patient health by enhancing the delivery of a therapeutic to its target …
products that improve patient health by enhancing the delivery of a therapeutic to its target …
Overview of the main anti-SARS-CoV-2 vaccines: mechanism of action, efficacy and safety
MT Mascellino, F Di Timoteo… - Infection and drug …, 2021 - Taylor & Francis
This review takes into consideration the principal vaccines developed against the SARS-
CoV-2 in this unprecedented period of Covid-19 pandemic. We evaluated the mechanism of …
CoV-2 in this unprecedented period of Covid-19 pandemic. We evaluated the mechanism of …
[HTML][HTML] The limitless future of RNA therapeutics
Recent advances in the generation, purification and cellular delivery of RNA have enabled
development of RNA-based therapeutics for a broad array of applications. RNA therapeutics …
development of RNA-based therapeutics for a broad array of applications. RNA therapeutics …
[PDF][PDF] Vaccine hesitancy, acceptance, and anti-vaccination: trends and future prospects for public health
An often-stated public health comment is that “vaccination is a victim of its own success.”
While the scientific and medical consensus on the benefits of vaccination is clear and …
While the scientific and medical consensus on the benefits of vaccination is clear and …
The impact of vaccination on coronavirus disease 2019 (COVID-19) outbreaks in the United States
Background Global vaccine development efforts have been accelerated in response to the
devastating coronavirus disease 2019 (COVID-19) pandemic. We evaluated the impact of a …
devastating coronavirus disease 2019 (COVID-19) pandemic. We evaluated the impact of a …
Aging in COVID-19: Vulnerability, immunity and intervention
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic was first
reported in Wuhan, China in December 2019, moved across the globe at an unprecedented …
reported in Wuhan, China in December 2019, moved across the globe at an unprecedented …
[HTML][HTML] What defines an efficacious COVID-19 vaccine? A review of the challenges assessing the clinical efficacy of vaccines against SARS-CoV-2
The novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),
has caused more than 1 million deaths in the first 6 months of the pandemic and huge …
has caused more than 1 million deaths in the first 6 months of the pandemic and huge …
Willingness to get the COVID-19 vaccine with and without emergency use authorization
Background This study assessed psychosocial predictors of US adults' willingness to get a
future COVID-19 vaccine and whether these predictors differ under an emergency use …
future COVID-19 vaccine and whether these predictors differ under an emergency use …