Goblet cells of the conjunctiva: A review of recent findings
IK Gipson - Progress in retinal and eye research, 2016 - Elsevier
Goblet cells within the conjunctival epithelium are specialized cells that secrete mucins onto
the surface of the eye. Recent research has demonstrated new characteristics of the cells …
the surface of the eye. Recent research has demonstrated new characteristics of the cells …
[HTML][HTML] Pathological and therapeutic roles of bioactive peptide trefoil factor 3 in diverse diseases: recent progress and perspective
Y Yang, Z Lin, Q Lin, W Bei, J Guo - Cell death & disease, 2022 - nature.com
Abstract Trefoil factor 3 (TFF3) is the last small-molecule peptide found in the trefoil factor
family, which is mainly secreted by intestinal goblet cells and exerts mucosal repair effect in …
family, which is mainly secreted by intestinal goblet cells and exerts mucosal repair effect in …
Single-cell analysis of endometriosis reveals a coordinated transcriptional programme driving immunotolerance and angiogenesis across eutopic and ectopic tissues
Endometriosis is characterized by the growth of endometrial-like tissue outside the uterus. It
affects many women during their reproductive age, causing years of pelvic pain and …
affects many women during their reproductive age, causing years of pelvic pain and …
Colitis-associated variant of TLR2 causes impaired mucosal repair because of TFF3 deficiency
DK Podolsky, G Gerken, A Eyking, E Cario - Gastroenterology, 2009 - Elsevier
BACKGROUND & AIMS: Goblet cells (GC) facilitate mucosal protection and epithelial barrier
repair, yet the innate immune mechanisms that selectively drive GC functions have not been …
repair, yet the innate immune mechanisms that selectively drive GC functions have not been …
Trefoil factor 2 rapidly induces interleukin 33 to promote type 2 immunity during allergic asthma and hookworm infection
M Wills-Karp, R Rani, K Dienger, I Lewkowich… - Journal of Experimental …, 2012 - rupress.org
The molecular mechanisms that drive mucosal T helper type 2 (TH2) responses against
parasitic helminths and allergens remain unclear. In this study, we demonstrate in mice that …
parasitic helminths and allergens remain unclear. In this study, we demonstrate in mice that …
Rotavirus infection induces glycan availability to promote ileum-specific changes in the microbiome aiding rotavirus virulence
MA Engevik, LD Banks, KA Engevik… - Gut …, 2020 - Taylor & Francis
Multiple studies have identified changes within the gut microbiome in response to diarrheal-
inducing bacterial pathogens. However, examination of the microbiome in response to viral …
inducing bacterial pathogens. However, examination of the microbiome in response to viral …
Lacritin and the tear proteome as natural replacement therapy for dry eye
Tear proteins are potential biomarkers, drug targets, and even biotherapeutics. As a
biotherapeutic, a recombinant tear protein might physiologically rescue the ocular surface …
biotherapeutic, a recombinant tear protein might physiologically rescue the ocular surface …
Epidermal growth factor containing culture supernatant enhances intestine development of early-weaned pigs in vivo: potential mechanisms involved
A Bedford, T Chen, E Huynh, C Zhu, S Medeiros… - Journal of …, 2015 - Elsevier
We have previously generated epidermal factor expressing Lactococcus lactis (EGF-LL)
using a bioengineering approach, and shown that EGF-LL fermentation supernatant …
using a bioengineering approach, and shown that EGF-LL fermentation supernatant …
Cardioprotective proteins upregulated in the liver in response to experimental myocardial ischemia
Myocardial ischemia (MI) activates innate cardioprotective mechanisms, enhancing
cardiomyocyte tolerance to ischemia. Here, we report a MI-activated liver-dependent …
cardiomyocyte tolerance to ischemia. Here, we report a MI-activated liver-dependent …
Structure, function, and therapeutic potential of the trefoil factor family in the gastrointestinal tract
N Braga Emidio, SM Brierley… - ACS Pharmacology & …, 2020 - ACS Publications
Trefoil factor family peptides (TFF1, TFF2, and TFF3) are key players in protecting,
maintaining, and repairing the gastrointestinal tract. Accordingly, they have the therapeutic …
maintaining, and repairing the gastrointestinal tract. Accordingly, they have the therapeutic …