Proper orchestration of the thousands of biochemical processes that are essential to the life
of every cell requires highly organized cellular compartmentalization of dedicated …

Cajal bodies (CBs) are distinct sub-nuclear structures that are present in eukaryotic living
cells and are often associated with the nucleolus. CBs play important roles in RNA …

GEMIN5 is essential for core assembly of small nuclear Ribonucleoproteins (snRNPs), the
building blocks of spliceosome formation. Loss-of-function mutations in GEMIN5 lead to a …

Type I spinal muscular atrophy (SMA) is an autosomal recessive disorder caused by loss or
mutations of the survival motor neuron 1 (SMN1) gene. The reduction in SMN protein levels …

Gene regulation ensures that the appropriate genes are expressed at the proper time.
Nuclear retention of incompletely spliced or mature mRNAs is emerging as a novel …

Last finding indicates that post-transcriptional processes are significant in low-oxygen
conditions, but their nature is poorly understood. Here, we localized poly (A) RNA and …

In microsporocytes of the European larch, we demonstrated the presence of several mRNAs
in spherical nuclear bodies. In the nuclei of microsporocytes, we observed up to 12 bodies …

Manuscript provides insights into the biology of long-lived plants, different from Arabidopsis,
tomato or grass species that are widely studied. In the European larch the diplotene stage …

Myotonic dystrophies (DM) are genetically based neuromuscular disorders characterized by
the accumulation of mutant transcripts into peculiar intranuclear foci, where different splicing …

Small nuclear ribonucleoproteins (snRNPs) play a crucial role in pre-mRNA splicing in all
eukaryotic cells. In contrast to the relatively broad knowledge on snRNP assembly within the …