Small RNAs are short non-coding RNAs with a length ranging between 20 and 24
nucleotides. Of these, microRNAs (miRNAs) play a distinct role in plant development …

Discoveries over the past decade portend a paradigm shift in molecular biology. Evidence
suggests that RNA is not only functional as a messenger between DNA and protein but also …

The ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic
creates a significant threat to global health. Recent studies suggested the significance of …

Small-RNA-guided gene regulation has emerged as one of the fundamental principles in
cell function, and the major protein players in this process are members of the Argonaute …

A conserved biological response to double-stranded RNA, known variously as RNA
interference (RNAi) or post-transcriptional gene silencing, mediates resistance to both …

MicroRNAs (miRNAs) interact with target mRNAs at specific sites to induce cleavage of the
message or inhibit translation. The specific function of most mammalian miRNAs is …

The enzyme Dicer is best known for its role as a riboendonuclease in the small RNA
pathway. In this canonical role, Dicer is a critical regulator of the biogenesis of microRNA …

For 50 years the term 'gene'has been synonymous with regions of the genome encoding
mRNAs that are translated into protein. However, recent genome‐wide studies have shown …

Gene silencing through RNA interference (RNAi) is carried out by RISC, the RNA-induced
silencing complex. RISC contains two signature components, small interfering RNAs …

Drosophila Piwi-family proteins have been implicated in transposon control. Here, we
examine piwi-interacting RNAs (piRNAs) associated with each Drosophila Piwi protein and …