Monkeypox is a self-limiting zoonotic viral disease and causes smallpox-like symptoms. The
disease has a case fatality ratio of 3–6% and, recently, a multi-country outbreak of the …

Canine circovirus (CanineCV) is a deadly pathogen affecting both domestic and wild
carnivores including dogs. No vaccine against CanineCV is available commercially or under …

Autophagy is a conserved adaptive cellular pathway essential to maintain a variety of
physiological functions. Core components of this machinery are the six human Atg8 …

The DNA repair capacity of human cells declines with age, in a process that is not clearly
understood. Mutation of the nuclear envelope protein barrier-to-autointegration factor 1 …

Gastrointestinal diarrhea is majorly caused by the rotavirus (RV) in the children who
generally are under the age group of 5 years. WHO estimates that∼ 95% of the children …

The crown of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
constituted by its spike (S) glycoprotein. S protein mediates the SARS-CoV-2 entry into the …

In view of the increasing interest both in inhibitors of protein-protein interactions and in
protein drugs themselves, analysis of the three-dimensional structure of protein-protein …

Background Study of macromolecular assemblies is fundamental to understand functions in
cells. X-ray crystallography is the most common technique to solve their 3D structure at …

Cystathionine γ-lyase (CGL) is a key enzyme in the methionine–cysteine cycle in all living
organisms forming cysteine, α-ketobutyrate and ammonia via homocysteine and …

As long as the structural study of molecular mechanisms requires multiple molecular
dynamics reflecting contrasted bioactive states, the subsequent analysis of molecular …