Minimal residual disease (MRD) assessment is incorporated in an increasing number of multiple myeloma (MM) clinical trials as a correlative analysis, an endpoint or even as a …
LJ Costa, S Chhabra, E Medvedova… - Journal of Clinical …, 2022 - ascopubs.org
PURPOSE The MASTER trial combined daratumumab, carfilzomib, lenalidomide, and dexamethasone (Dara-KRd) in newly diagnosed multiple myeloma (NDMM), using minimal …
The prognostic value of minimal residual disease (MRD) for progression-free survival (PFS) and overall survival (OS) was evaluated in a large cohort of patients with multiple myeloma …
B Paiva, N Puig, MT Cedena, L Rosiñol… - Journal of Clinical …, 2020 - ascopubs.org
PURPOSE Assessing measurable residual disease (MRD) has become standard with many tumors, but the clinical meaning of MRD in multiple myeloma (MM) remains uncertain …
E Zamagni, C Nanni, L Dozza, T Carlier… - Journal of Clinical …, 2021 - ascopubs.org
PURPOSE 18F-Fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) is currently the standard technique to define minimal residual disease …
I Goicoechea, N Puig, MT Cedena… - Blood, The Journal …, 2021 - ashpublications.org
Patients with multiple myeloma (MM) carrying standard-or high-risk cytogenetic abnormalities (CAs) achieve similar complete response (CR) rates, but the later have inferior …
SK Kumar, NS Callander, J Hillengass… - Journal of the National …, 2019 - jnccn.org
The NCCN Guidelines for Multiple Myeloma provide recommendations for diagnosis, workup, treatment, follow-up, and supportive care for patients with monoclonal gammopathy …
Abstract Deciphering Multiple Myeloma evolution in the whole bone marrow is key to inform curative strategies. Here, we perform spatial-longitudinal whole-exome sequencing …
The development of novel agents has transformed the treatment paradigm for multiple myeloma, with minimal residual disease (MRD) negativity now achievable across the entire …