New anticonvulsant agents

B Malawska - Frontiers in Medicinal Chemistry: Volume 4, 2009 - benthamdirect.com
The search for antiepileptic compounds with more selective activity and lower toxicity
continues to be an area of intensive investigation in medicinal chemistry. This review …

Recent development in preparation reactivity and biological activity of enaminoketones and enaminothiones and their utilization to prepare heterocyclic compounds

G Negri, C Kascheres… - Journal of heterocyclic …, 2004 - Wiley Online Library
Enaminoketones and esters are gaining increased interest, particularly cyclic‐β‐
enaminoesters, which are known as important intermediates for the synthesis of …

A new copper-based metal–organic framework as a promising heterogeneous catalyst for chemo-and regio-selective enamination of β-ketoesters

Y Zhao, DS Deng, LF Ma, BM Ji… - Chemical Communications, 2013 - pubs.rsc.org
Assembly of 5-nitro-1, 2, 3-benzenetricarboxylic acid (H3nbta) with CuII in the presence of 1,
3-bis (1, 2, 4-triazol-1-yl) propane (1, 3-btp) leads to a new metal–organic framework,[Cu …

Electrochemical synthesis of enaminones via a decarboxylative coupling reaction

X Kong, Y Liu, L Lin, Q Chen, B Xu - Green Chemistry, 2019 - pubs.rsc.org
An environmentally benign and efficient electrochemical synthesis of enaminones via a
decarboxylative coupling reaction of α-keto acids using n-Bu4NI as a redox catalyst and …

[PDF][PDF] Amberlyst-15 in organic synthesis

R Pal, T Sarkar, S Khasnobis - Arkivoc, 2012 - arkat-usa.org
Commercially available Amberlyst-15 has played an important role in organic synthesis.
This review summarizes the versatile synthetic applications of Amberlyst-15 in different …

Rhodium(III)-Catalyzed Coupling of Quinolin-8-carboxaldehydes with CF3–Imidoyl Sulfoxonium Ylides by Chelation-Assisted C(sp2)-H Bond Activation for the …

P Li, Z Yang, Z Chen - The Journal of Organic Chemistry, 2024 - ACS Publications
A rhodium (III)-catalyzed aldehydic C (sp2)–H imidoylmethylation of quinolin-8-
carboxaldehydes with CF3-imidoyl sulfoxonium ylides (TFISYs) has been developed for the …

Highly Selective MOF-Based Turn-Off Luminescence Detection of Hg2+ Ions in an Aqueous Medium and Its Dual Functional Catalytic Activity toward Aldol …

K Manna, S Natarajan - Inorganic Chemistry, 2022 - ACS Publications
A new organic ligand, 5-(carboxyformamido) isophthalic acid (5-CFIA), was prepared and
employed for the synthesis of two compounds [M3 (C10H4O7N1) 2 (8H2O)]· H2O (M= Cd …

Synthesis of enaminones via copper-catalyzed decarboxylative coupling reaction under redox-neutral conditions

Z Zhu, X Tang, J Li, X Li, W Wu, G Deng… - Chemical …, 2017 - pubs.rsc.org
A novel copper-catalyzed C (sp3)–H oxidative functionalization of aromatic oxime acetates
with α-oxocarboxylic acids was reported. This process involved N–O/C–C bond cleavages …

Enaminones: Exploring additional therapeutic activities

IO Edafiogho, SB Kombian… - Journal of …, 2007 - Elsevier
Enaminones, enamines of β‐dicarbonyl compounds, have been known for many years.
Their early use has been relegated to serving as synthetic intermediates in organic …

Electrochemical Transformations of Enamines: Recent Advances and Future Perspectives

D Li, L Chen - European Journal of Organic Chemistry, 2024 - Wiley Online Library
Enamines, containing nucleophilic amino groups and activated C= C bonds, are important
building blocks, and widely used in the synthesis of heterocycles, natural products, and …