Local Control Model of a Human Ventricular Myocyte: An Exploration of Frequency-Dependent Changes and Calcium Sparks
Calcium (Ca2+) sparks are the elementary events of excitation–contraction coupling, yet
they are not explicitly represented in human ventricular myocyte models. A stochastic …
they are not explicitly represented in human ventricular myocyte models. A stochastic …
Ventricular Tachycardia Due to Triggered Activity: Role of Early and Delayed Afterdepolarizations
Most forms of sustained ventricular tachycardia (VT) are caused by re-entry, resulting from
altered myocardial conduction and refractoriness secondary to underlying structural heart …
altered myocardial conduction and refractoriness secondary to underlying structural heart …
Pathophysiology, molecular mechanisms, and genetics of atrial fibrillation
P Han, X Zhao, X Li, J Geng, S Ni, Q Li - Human Cell, 2025 - Springer
The development of atrial fibrillation (AF) is a highly complex, multifactorial process involving
pathophysiologic mechanisms, molecular pathway mechanisms and numerous genetic …
pathophysiologic mechanisms, molecular pathway mechanisms and numerous genetic …
Pacing Dynamics Determines the Arrhythmogenic Mechanism of the CPVT2-Causing CASQ2G112+5X Mutation in a Guinea Pig Ventricular Myocyte Computational …
Calsequestrin Type 2 (CASQ2) is a high-capacity, low-affinity, Ca2+-binding protein
expressed in the sarcoplasmic reticulum (SR) of the cardiac myocyte. Mutations in CASQ2 …
expressed in the sarcoplasmic reticulum (SR) of the cardiac myocyte. Mutations in CASQ2 …
Intra-and Inter-Individual Cardiomyocyte Heterogeneity Impacts Arrhythmia Risk
TK Pullinger - 2024 - search.proquest.com
Heterogeneity has been shown to impact resilience in a range of complex systems,
including the heart. Cardiac heterogeneity takes many forms including structural …
including the heart. Cardiac heterogeneity takes many forms including structural …