Guardians of the gut: influence of the enteric nervous system on the intestinal epithelial barrier

M Bubeck, C Becker, JV Patankar - Frontiers in Medicine, 2023 - frontiersin.org
The intestinal mucosal surface forms one of the largest areas of the body, which is in direct
contact with the environment. Co-ordinated sensory functions of immune, epithelial, and …

[HTML][HTML] Cellular and molecular mechanisms of intestinal fibrosis

X Wu, X Lin, J Tan, Z Liu, J He, F Hu, Y Wang… - Gut and …, 2023 - ncbi.nlm.nih.gov
Intestinal fibrosis associated stricture is a common complication of inflammatory bowel
disease usually requiring endoscopic or surgical intervention. Effective anti-fibrotic agents …

Comprehensive review and update of stricturing Crohn's disease

AT Elford, Z Ardalan, P Simkin… - Indian Journal of …, 2024 - Springer
Up to 50% of patients with Crohn's disease develop a stricture within 10 years of diagnosis.
Crohn's strictures can compose of inflammation, fibrosis or smooth muscle expansion and …

How to evaluate fibrosis in IBD?

H Tavares de Sousa, F Magro - Diagnostics, 2023 - mdpi.com
In this review, we will describe the importance of fibrosis in inflammatory bowel disease
(IBD) by discussing its distinct impact on Crohn's disease (CD) and ulcerative colitis (UC) …

Intestinal strictures in Crohn's disease: a 2021 update

X Lin, Y Wang, Z Liu, S Lin, J Tan, J He… - Therapeutic …, 2022 - journals.sagepub.com
Intestinal strictures remain one of the most intractable and common complications of Crohn's
disease (CD). Approximately 70% of CD patients will develop fibrotic strictures after 10 years …

[HTML][HTML] Resistance to apoptosis in complicated Crohn's disease: Relevance in ileal fibrosis

M Seco-Cervera, D Ortiz-Masiá… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Background and aims The stiffening of the extracellular matrix, and changes in its cellular
and molecular composition, have been reported in the pathogenesis of fibrosis. We analyze …

Contemporary Imaging Assessment of Strictures and Fibrosis in Crohn Disease, With Focus on Quantitative Biomarkers: From the AJR Special Series on Imaging of …

J Rimola, KJ Beek, I Ordás, KB Gecse… - American Journal of …, 2023 - Am Roentgen Ray Soc
Patients with Crohn disease commonly have bowel strictures develop, which exhibit varying
degrees of inflammation and fibrosis. Differentiation of the distinct inflammatory and fibrotic …

The effects of mesenteric inflammation on intestinal fibrosis

R Mao, Z Liu, F Rieder - The Mesentery and inflammation, 2023 - Springer
Characterized by chronic intestinal inflammation, Crohn's disease patients frequently suffer
from complications of intestinal fibrostenosis. In recent years, the mesenteric inflammation in …

Advances in endoscopy for pediatric inflammatory bowel disease

N Carman, JA Picoraro - Gastrointestinal Endoscopy Clinics, 2023 - giendo.theclinics.com
Endoscopy in the field of inflammatory bowel disease (IBD) has remained the cornerstone of
diagnostic assessment and disease monitoring for both adult and pediatric patients. As our …

Interventional inflammatory bowel disease: endoscopic therapy of complications of Crohn's disease

B Shen - Gastroenterology Report, 2022 - academic.oup.com
Endoscopic therapy for inflammatory bowel diseases (IBD) or IBD surgery-associated
complications or namely interventional IBD has become the main treatment modality for …