Bioluminescence has long been used to image biological processes in vivo. This technology
features luciferase enzymes and luciferin small molecules that produce visible light …

Bioluminescence (BL) relies on the enzymatic reaction between luciferase, a substrate
conventionally named luciferin, and various cofactors. BL imaging has become a widely …

Highlights•Advances in bioluminescent tool production that mirror trends in fluorescent
probe development.•New bioluminescent platforms based on naturally occurring luciferases …

Bioluminescence imaging (BLI) is a newly developed noninvasive visual approach which
facilitates the understanding of a plethora of biological processes in vitro and in vivo due to …

Bioluminescence imaging with luciferase–luciferin pairs is a well-established technique for
visualizing biological processes across tissues and whole organisms. Applications at the …

Conspectus Bioluminescence is widely used for real-time imaging in living organisms. This
technology features a light-emitting reaction between enzymes (luciferases) and small …

Multi-component bioluminescence imaging requires an expanded collection of luciferase–
luciferin pairs that emit far-red or near-infrared light. Toward this end, we prepared a new …

Antibiotic resistance is an alarming public health concern that affects millions of individuals
across the globe each year. A major challenge in the development of effective antibiotics lies …

Genetically encodable sensors have been widely used in the detection of intracellular
molecules ranging from metal ions and metabolites to nucleic acids and proteins. These …

Many fluorophores, and all bright light-emitting substrates for firefly luciferase, contain
hydroxyl or amine electron donors. Sulfonamides were found to be capable of serving as …