Acute cerebellar inflammation and related ataxia: mechanisms and pathophysiology

MSA Parvez, G Ohtsuki - Brain sciences, 2022 - mdpi.com
The cerebellum governs motor coordination and motor learning. Infection with external
microorganisms, such as viruses, bacteria, and fungi, induces the release and production of …

[HTML][HTML] Stable continual learning through structured multiscale plasticity manifolds

P Mishra, R Narayanan - Current opinion in neurobiology, 2021 - Elsevier
Biological plasticity is ubiquitous. How does the brain navigate this complex plasticity space,
where any component can seemingly change, in adapting to an ever-changing …

VTA-projecting cerebellar neurons mediate stress-dependent depression-like behaviors

SJ Baek, JS Park, J Kim, Y Yamamoto… - Elife, 2022 - elifesciences.org
Although cerebellar alterations have been implicated in stress symptoms, the exact
contribution of the cerebellum to stress symptoms remains to be elucidated. Here, we …

[HTML][HTML] Association between sleep slow-wave activity and in-vivo estimates of myelin in healthy young men

M Deantoni, M Baillet, G Hammad, C Berthomier… - Neuroimage, 2023 - Elsevier
Sleep has been suggested to contribute to myelinogenesis and associated structural
changes in the brain. As a principal hallmark of sleep, slow-wave activity (SWA) is …

Inflammatory, synaptic, motor, and behavioral alterations induced by gestational sepsis on the offspring at different stages of life

MG Granja, LP Alves, M Leardini-Tristão… - Journal of …, 2021 - Springer
Background The term sepsis is used to designate a systemic condition of infection and
inflammation associated with hemodynamic changes that result in organic dysfunction …

[HTML][HTML] Microglia-triggered hypoexcitability plasticity of pyramidal neurons in the rat medial prefrontal cortex

Y Yamawaki, Y Wada, S Matsui, G Ohtsuki - Current Research in …, 2022 - Elsevier
Lipopolysaccharide (LPS), an outer component of Gram-negative bacteria, induces a strong
response of innate immunity via microglia, which triggers a modulation of the intrinsic …

Network motifs in cellular neurophysiology

D Mittal, R Narayanan - Trends in Neurosciences, 2024 - cell.com
Abstract Concepts from network science and graph theory, including the framework of
network motifs, have been frequently applied in studying neuronal networks and other …

Immune-triggered forms of plasticity across brain regions

M Hikosaka, T Kawano, Y Wada, T Maeda… - Frontiers in Cellular …, 2022 - frontiersin.org
Immune cells play numerous roles in the host defense against the invasion of
microorganisms and pathogens, which induces the release of inflammatory mediators (eg …

Psychosis symptoms following aberrant immunity in the brain

A Ozaki, Y Yamawaki, G Ohtsuki - Neural Regeneration Research, 2021 - journals.lww.com
Neuroinflammation in the brain is thought related to the emergence of various psychoses,
although the identifying regional significance, the involvement of immune-cells and …

A destruction model of the vascular and lymphatic systems in the emergence of psychiatric symptoms

K Segawa, Y Blumenthal, Y Yamawaki, G Ohtsuki - Biology, 2021 - mdpi.com
Simple Summary Impairment of the immune-barrier system in the aged brain is manifested
in neurodegenerative diseases, such as Alzheimer's disease. Cerebrospinal fluid flow and …