The adhesive interactions of cells with other cells and with the extracellular matrix are crucial
to all developmental processes, but have a central role in the functions of the immune …

Angiogenesis, or the formation of new blood vessels out of pre-existing capillaries, is a
sequence of events that is fundamental to many physiologic and pathologic processes such …

An inducible rabbit endothelial adhesion molecule that is selective for mononuclear
leukocytes has been identified. This adhesion protein was expressed on the surface of …

Rolling of leukocytes on vascular endotheliai cells, an early event in inflammation, can be
reproduced in vitro on artificial lipid bilayers containing purified CD62, a seiectln also named …

We have identified two compounds that inhibit the expression of endothelial-leukocyte
adhesion molecules intercellular adhesion molecule-1, vascular cell adhesion molecule-1 …

While an elevated plasma concentration of HDLs is protective against the development of
atherosclerosis and ensuing coronary heart disease (CHD), the mechanism of this …

Interactions between CD8+ T cells and endothelial cells are important in both protective and
pathologic immune responses. Endothelial cells regulate the recruitment of CD8+ Tcells into …

While the leukocyte integrin lymphocyte function-associated antigen (LFA)-1 has been
demonstrated to bind intercellular adhesion molecule (ICAM)-1, results with the related Mac …

Accumulation of monocyte-derived foam cells in focal areas of the arterial intima is one of
the key events in early atherogenesis. We have examined the effect of …

The primary function of neutrophils in host defense is to contain and eradicate invading
microbial pathogens. This is achieved through a series of swift and highly coordinated …