The Transforming Growth Factor-beta (TGF-β) family plays relevant roles in the regulation of
different cellular processes that are essential for tissue and organ homeostasis. In the case …

The epithelial to mesenchymal transition (EMT) is a multistep biological process whereby
epithelial cells change in plasticity by transient de-differentiation into a mesenchymal …

Transforming growth factor-β (TGF-β) is a cytokine essential for the induction of the fibrotic
response and for the activation of the cancer stroma. Strong evidence suggests that a strong …

Transforming growth factor-β (TGFβ) suppresses tumor formation since it inhibits cell growth
and promotes apoptosis. However, in advanced cancers TGFβ elicits tumor promoting …

Bioprinting is an emergent technology that has already demonstrated the capacity to create
complex and/or vascularized multicellular structures with defined and organized …

Cancer stem cells (CSCs) are cells within a tumor that possess the capacity to self-renew
and maintain tumor-initiating capacity through differentiation into the heterogeneous …

Autophagy is a highly conserved cellular process by which cytoplasmic components are
sequestered in autophagosomes and delivered to lysosomes for degradation. As a major …

The oncofetal H19 gene transcribes a long non-coding RNA (lncRNA) that is essential for
tumor growth. Here we found that numerous established inducers of epithelial to …

Genome-wide association studies and follow-up meta-analyses in Crohn's disease (CD)
and ulcerative colitis (UC) have recently identified 163 disease-associated loci that meet …

The transforming growth factor-beta (TGF-!) belongs to a superfamily of cytokines that act on
protein kinase receptors at the plasma membrane to induce a plethora of biological signals …