In the last 10 years, we have learned much about the pathogenesis, diagnosis, and
management of intestinal fibrosis in patients with inflammatory bowel diseases. Just a …

The intestinal extracellular matrix (ECM) represents a complex network of proteins that not
only forms a support structure for resident cells but also interacts closely with them by …

The global prevalence of cancer is increasing, largely as more patients are living into old
age. Therefore, gastroenterologists caring for patients with inflammatory bowel disease [IBD] …

Background Human umbilical cord mesenchymal stem cell (hucMSC)-derived exosomes
are recognized as novel cell-free therapeutic agents for inflammatory bowel disease (IBD), a …

Background & Aims Intestinal fibrosis is a long-term complication in inflammatory bowel
diseases (IBD) that frequently results in functional damage, bowel obstruction, and surgery …

As a main digestive organ and an important immune organ, the intestine plays a vital role in
resisting the invasion of potential pathogens into the body. Intestinal immune dysfunction …

Abstract Nrf2 (nuclear factor erythroid 2-related factor 2) is a stress-responsive transcription
factor, associated with cellular homeostasis. Under normal conditions Nrf2 is kept in the …

This ECCO topical review of the European Crohn's and Colitis Organisation [ECCO] focused
on prediction, diagnosis, and management of fibrostenosing Crohn's disease [CD]. The …

Matrix metalloproteinases (MMPs) are known to be upregulated in inflammatory bowel
disease (IBD) and other inflammatory conditions, but while their involvement is clear, their …

Intestinal fibrosis is a common complication of the inflammatory bowel diseases (IBDs). It
becomes clinically apparent in> 30% of patients with Crohn's disease (CD) and in about 5 …